4-(P-tolyl)-5-(3,4,5-trimethoxyphenyl)-4h-1,2,4-triazole-3-thiol CAS 305336-64-5
| CAS No. | 305336-64-5 |
| Molecular Formula | C18H19N3O3S |
| Molecular Weight | 357.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(P-tolyl)-5-(3,4,5-trimethoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 305336-64-5), molecular formula C18H19N3O3S and molecular weight 357.43 g/mol, is a CATO reference standard with documented purity and traceability.
4-(P-tolyl)-5-(3,4,5-trimethoxyphenyl)-4h-1,2,4-triazole-3-thiol (C18H19N3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19N3O3S |
| Molecular Weight | 357.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related P Standards
- P-tolyl(1-(4-(p-tolyl)pyrimidin-2-yl)-1H-1,2,3-triazol-4-yl)methanone (CAS 882747-54-8)
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Recommended Standards
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- Zinc Cyanide (CAS 557-21-1)
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- 1,4-Dihydropyrido[2,3-b]pyrazine-2,3-dione (CAS 2067-84-7)
- Ethyl 7-bromo-2,4-dichloro-1,5-naphthyridine-3-carboxylate (CAS 2758819-88-2)
- 3-Methoxy-2-methylbenzyl chloride (CAS 42981-94-2)
- 4-Ethoxy-3,5-difluorobenzamide (CAS 1017779-23-5)
- 2-((4-Fluorophenyl)thio)-N-(4-methylbenzo[d]thiazol-2-yl)acetamide (CAS 895490-16-1)
- 6-Oxopiperidine-3-carboxylic Acid (CAS 22540-50-7)
- (1S,2S)-2-(1-Pyrrolidinyl)cyclohexanamine (CAS 824938-97-8)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
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