4-[4-(4-Methoxybenzenesulfonyl)piperazin-1-yl]benzonitrile CAS 478046-93-4
| CAS No. | 478046-93-4 |
| Molecular Formula | C18H19N3O3S |
| Molecular Weight | 357.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-[4-(4-Methoxybenzenesulfonyl)piperazin-1-yl]benzonitrile (CAS 478046-93-4), molecular formula C18H19N3O3S and molecular weight 357.43 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 4-[4-(4-Methoxybenzenesulfonyl)piperazin-1-yl]benzonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 357.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19N3O3S |
| Molecular Weight | 357.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methoxybenzenesulfonyl Standards
- 4-[4-(4-methoxybenzenesulfonyl)piperazin-1-yl]-4-oxobutanoic acid (CAS 893725-62-7)
- Ethyl 2-[1-(4-methoxybenzenesulfonyl)-3-oxopiperazin-2-yl]acetate (CAS 318469-58-8)
- 2-[4-(4-Methoxybenzenesulfonyl)-3,4-dihydro-2H-1,4-benzoxazin-3-yl]acetic acid (CAS 865657-74-5)
- 2-(4-Methoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 191326-98-4)
- (2S)-2-{[1-(4-methoxybenzenesulfonyl)piperidin-4-yl]formamido}propanoic acid (CAS 1212420-14-8)
- 4-(4-Methoxybenzenesulfonyl)-3-phenyl-3,4-dihydro-2H-1,4-benzoxazine (CAS 338962-42-8)
- Ethyl 2-[1-(4-methoxybenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-2-oxoacetate (CAS 860612-17-5)
- 5-[1-(4-Methoxybenzenesulfonyl)-1H-pyrazol-3-yl]-2-phenyl-1,3-thiazole (CAS 318248-78-1)
Recommended Standards
- 4-(P-tolyl)-5-(3,4,5-trimethoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 305336-64-5)
- 4-Amino-6,7-dimethoxy-3-(4-methoxybenzyl)quinazoline-2(3H)-thione (CAS 439096-59-0)
- 3-(2-Cyano-4,5-dimethoxyphenyl)-1-[(2-methoxyphenyl)methyl]thiourea (CAS 692287-64-2)
- 4-Methyl-3,5-diphenyl-1H-pyrazol-1-yl dimethylsulfamate (CAS 400084-12-0)
- 1-(4-Bromo-3-methylphenyl)guanidine (CAS 1250558-19-0)
- tert-Butyl (2R,4R)-4-hydroxy-2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate (CAS 2325666-08-6)
- 5-Bromo-8-chloro-2-hydroxyquinolin-4(1H)-one (CAS 1996052-61-9)
- 6-Fluoro-2,3-dihydro-1H-inden-1-one (CAS 1481-32-9)
- 3-(1-Ethyl-1h-pyrazol-5-yl)propanoic acid (CAS 1006483-07-3)
- (Z)-N'-Hydroxyfuran-2-carboximidamide hydrochloride (CAS 154346-10-8)
- 4-Cyclopropoxy-N,N,2-trimethylnicotinamide (CAS 1243311-12-7)
- 3,4-Dichloro-8-methoxyquinoline (CAS 16797-43-6)
- (2R,3R)-2-methyl-3-(methylsulfonylmethyl)azetidine;hydrochloride (CAS 2725774-19-4)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com