N-{4-[(4-Fluorobenzyl)oxy]benzyl}-4-(trifluoromethoxy)aniline CAS 306730-31-4
| CAS No. | 306730-31-4 |
| Molecular Formula | C21H17F4NO2 |
| Molecular Weight | 391.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-{4-[(4-Fluorobenzyl)oxy]benzyl}-4-(trifluoromethoxy)aniline (CAS 306730-31-4), a certified reference material (molecular formula C21H17F4NO2, MW 391.36 g/mol) for analytical method development and quality control.
N-{4-[(4-Fluorobenzyl)oxy]benzyl}-4-(trifluoromethoxy)aniline (C21H17F4NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-{4-[(4-Fluorobenzyl)oxy]benzyl}-4-(trifluoromethoxy)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H17F4NO2 |
| Molecular Weight | 391.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 1-(4-Fluorobenzyl)-N-(2-fluorophenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 946352-97-2)
- (3-(2-((4-Fluorobenzyl)oxy)phenyl)-1H-pyrazol-1-yl)(4-fluorophenyl)methanone (CAS 477713-48-7)
- N-(4-fluorobenzyl)-4-(3-(trifluoromethyl)benzoyl)-1H-pyrrole-2-carboxamide (CAS 439111-42-9)
- (4-(4-Fluorobenzyl)-4-hydroxypiperidin-1-yl)(2-(pyrimidin-4-yl)pyridin-3-yl)methanone (CAS 1429505-54-3)
- 2-((4-Fluorobenzyl)thio)-5-(thieno[2,3-b]quinolin-2-yl)-1,3,4-oxadiazole (CAS 692737-18-1)
- 2-((4-Fluorobenzyl)thio)-1-(o-tolyl)-5-(p-tolyl)-1H-imidazole (CAS 1207026-85-4)
- 2-((4-Fluorobenzyl)thio)-1,5-di-p-tolyl-1H-imidazole (CAS 1207042-56-5)
- 3-((4-Fluorobenzyl)thio)-1-(p-tolyl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 691868-94-7)
Recommended Standards
- N-[(2Z)-3-tert-Butyl-4-(4-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-ylidene]-1-(4-chlorophenyl)methanamine (CAS 866010-07-3)
- Perfluorophenyl 1-(thiophen-2-ylmethyl)piperidine-4-carboxylate (CAS 930111-06-1)
- Levofloxacin Desethylene Diformyl Impurity (CAS 151377-74-1)
- 1,3-Bis(tert-butoxycarbonyl)-2-(trifluoromethanesulfonyl)guanidine 1,3-Bis(tert-butoxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine 1,3-Di-Boc-2-(trifluoromethanesulfonyl)guanidine 1,3-Di-Boc-2-(trifluoromethylsulfonyl)guanidine 207857-15-6 B3625 Goodman's Reagent (CAS 207857-15-6)
- 376592-43-7 5'-Fluoro-2'-methoxy[1,1'-biphenyl]-3-carboxylic acid DTXSID60680822 (CAS 376592-43-7)
- (2s)-2-(4-Methoxyphenyl)propanoic acid (CAS 24470-14-2)
- 2-((5-(4-Fluorophenyl)-1,2,4-triazin-3-yl)thio)benzoic acid (CAS 87992-31-2)
- 5-(4-Amidinophenoxy)pentanoic Acid (CAS 144602-61-9)
- 2-Chloro-3-cyano-6-(difluoromethyl)pyridine-4-sulfonamide (CAS 1805258-16-5)
- Berberine Impurity 31 (CAS 17388-19-1)
- (3-(Azetidin-1-ylmethyl)phenyl)(2-(trifluoromethyl)phenyl)methanone (CAS 898771-91-0)
- 3-Chloro-6-(4-fluorophenyl)pyridazine (CAS 66548-52-5)
- Tert-butyl 4-[1-(4-fluorophenyl)-2-methoxy-2-oxoethyl]piperazine-1-carboxylate (CAS 191033-99-5)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com