3-Phenyl-5-(piperazin-1-yl)-1,2,4-thiadiazole CAS 306935-14-8
| CAS No. | 306935-14-8 |
| Molecular Formula | C12H14N4S |
| Molecular Weight | 246.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Phenyl-5-(piperazin-1-yl)-1,2,4-thiadiazole (C12H14N4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Phenyl-5-(piperazin-1-yl)-1,2,4-thiadiazole (CAS 306935-14-8) is a high-purity analytical reference standard with the molecular formula C12H14N4S and a molecular weight of 246.33 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N4S |
| Molecular Weight | 246.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-Cyclopentyl-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 331971-79-0)
- 4-(4-phenyl-1,3-thiazol-2-yl)morpholine (CAS 19983-28-9)
- 3-Benzyl-5-(propan-2-ylidene)-2-thioxoimidazolidin-4-one (CAS 61632-46-0)
- 4-Cyclopentyl-5-(pyridin-4-yl)-4h-1,2,4-triazole-3-thiol (CAS 672342-05-1)
- [[1-(4-Methoxyphenyl)-1h-tetrazol-5-yl]methyl]amine hydrochloride (CAS 1177311-29-3)
- 2-((4-Chlorobenzyl)thio)-4,5-diphenyl-1H-imidazole (CAS 338412-77-4)
- DIBP，DEHP In Polyvinyl Chloride (CAS CATO-CCRM101001)
- Ethyl 3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-2-carboxylate (CAS 882240-59-7)
- 6-Fluoro-2-hydroxy-3-nitrobenzaldehyde (CAS 38225-97-7)
- 4-Cyclopropoxy-5-methoxypicolinonitrile (CAS 1243451-16-2)
- 6-Bromo-3-oxoindane-5-carbonitrile (CAS 1156467-77-4)
- N,6-Dimethyl-2-morpholin-4-ylpyrimidin-4-amine (CAS 381716-92-3)
- Fingolimod-D4 Hydrochloride (CAS 1346604-90-7)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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