3-(4-Nitro-3-(trifluoromethyl)phenoxy)-N-(4-(trifluoromethyl)phenyl)thiophene-2-carboxamide CAS 306977-63-9
| CAS No. | 306977-63-9 |
| Molecular Formula | C19H10F6N2O4S |
| Molecular Weight | 476.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 476.35 g/mol gives 3-(4-Nitro-3-(trifluoromethyl)phenoxy)-N-(4-(trifluoromethyl)phenyl)thiophene-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(4-Nitro-3-(trifluoromethyl)phenoxy)-N-(4-(trifluoromethyl)phenyl)thiophene-2-carboxamide (CAS 306977-63-9) is a high-purity analytical reference standard with the molecular formula C19H10F6N2O4S and a molecular weight of 476.35 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 3-(4-Nitro-3-(trifluoromethyl)phenoxy)-N-(4-(trifluoromethyl)phenyl)thiophene-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 476.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Nitro-3-(trifluoromethyl)phenoxy)-N-(4-(trifluoromethyl)phenyl)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H10F6N2O4S |
| Molecular Weight | 476.35 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-Bromo-N-(3-(3-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzamide (CAS 891124-92-8)
- Ethyl 2-(2-((4-(4-bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)acetate (CAS 578754-67-3)
- Cxcr2-in-1 (CAS 1873376-49-8)
- (2S,4S)-4-(4-Benzyl-2-bromophenoxy)-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid (CAS 1354486-58-0)
- Methyl 3-iodo-4-methylthiophene-2-carboxylate (CAS 845878-92-4)
- 5-[(4-Iodo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2-furoic acid (CAS 1171235-93-0)
- Methyl (S)-2-(benzylamino)hexanoate hydrochloride (CAS 1122017-35-9)
- Eravacycline impurity 21 (CAS CATO-C4X-293821)
- 7-Chloro-1-(prop-2-yn-1-yl)quinolin-2(1H)-one (CAS 1420792-18-2)
- 3-(2-Morpholin-4-yl-5-trifluoromethyl-pyridin-3-yl)-benzoic acid methyl ester (CAS 1311279-51-2)
- N-(((2R,3R)-2-isopropyltetrahydrofuran-3-yl)methyl)thietan-3-amine (CAS 1867634-89-6)
- 5-(2-Chlorophenyl)-3-(p-tolyl)-1H-pyrazole (CAS 1621488-10-5)
- [(2,4-Dichlorophenyl)methyl](2-methylpropyl)amine (CAS 869947-67-1)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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