6-(2-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile CAS 306977-96-8
| CAS No. | 306977-96-8 |
| Molecular Formula | C18H10ClFN2O |
| Molecular Weight | 324.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(2-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(2-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile (CAS 306977-96-8), molecular formula C18H10ClFN2O and molecular weight 324.74 g/mol, is a CATO reference standard with documented purity and traceability.
6-(2-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile (C18H10ClFN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-(2-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10ClFN2O |
| Molecular Weight | 324.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 4-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile (CAS 339103-70-7)
- 4-(4-Chlorophenyl)-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 866143-57-9)
- 5-(4-Chlorophenyl)-2-(4-fluorophenoxy)nicotinonitrile (CAS 338954-69-1)
- 6-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile (CAS 252059-12-4)
- 1-(4-Chlorophenyl)-4-ethoxy-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 138679-22-8)
- 2-(2-(4-Chlorophenyl)-2-oxoethyl)-3-methylnaphthalene-1,4-dione (CAS 329234-64-2)
- 3-(2-Chlorophenyl)-N-(2,2-dimethoxyethyl)-5-methylisoxazole-4-carboxamide (CAS 497060-42-1)
- 3-(3-(4-Chlorophenyl)-1-phenyl-1h-pyrazol-4-yl)acrylic acid (CAS 55432-14-9)
Recommended Standards
- 6-((5-Chloro-3-methylbenzofuran-2-yl)sulfonyl)pyridazin-3(2H)-one (CAS 463976-07-0)
- 5-Fluoro-1-(quinolin-4-yl)-1H-indole-3-carbonyl chloride (CAS 649550-99-2)
- Bis(2,6-dimethylphenyl) phosphorochloridate (CAS 81639-99-8)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carbothioamide (CAS 303150-11-0)
- 5'-Chloro-3'H-spiro[azetidine-3,1'-isobenzofuran] (CAS 2412552-84-0)
- 4-(3,4-Difluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride (CAS 574007-39-9)
- 6-(Thiophen-3-yl)nicotinonitrile (CAS 937601-80-4)
- 3-Propoxyaniline (CAS 4469-79-8)
- 2,2'-Sulfonylbis(nitrobenzene) (CAS 14665-52-2)
- Methyl 4-chloro-6-(hydroxymethyl)picolinate (CAS 109880-43-5)
- 2-Carboxyethyl acrylate oligomer (CAS 117647-40-2)
- Faropenem Impurity 21 (CAS CATO-C4X-128921)
- 3-Bromo-2-(((4-phenyl-4H-1,2,4-triazol-3-yl)thio)methyl)imidazo[1,2-a]pyridine (CAS 299955-42-3)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
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