4-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile CAS 339103-70-7
| CAS No. | 339103-70-7 |
| Molecular Formula | C18H10ClFN2O |
| Molecular Weight | 324.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile.
4-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile (CAS 339103-70-7) is a high-purity analytical reference standard with the molecular formula C18H10ClFN2O and a molecular weight of 324.74 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 324.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10ClFN2O |
| Molecular Weight | 324.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 4-(4-Chlorophenyl)-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 866143-57-9)
- 5-(4-Chlorophenyl)-2-(4-fluorophenoxy)nicotinonitrile (CAS 338954-69-1)
- 6-(2-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile (CAS 306977-96-8)
- 6-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile (CAS 252059-12-4)
- 1-(4-Chlorophenyl)-4-ethoxy-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 138679-22-8)
- 2-(2-(4-Chlorophenyl)-2-oxoethyl)-3-methylnaphthalene-1,4-dione (CAS 329234-64-2)
- 3-(2-Chlorophenyl)-N-(2,2-dimethoxyethyl)-5-methylisoxazole-4-carboxamide (CAS 497060-42-1)
- 3-(3-(4-Chlorophenyl)-1-phenyl-1h-pyrazol-4-yl)acrylic acid (CAS 55432-14-9)
Recommended Standards
- (E)-2-((2-chloro-6-fluorobenzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-38-4)
- (E)-2-((2-chloro-4-fluorobenzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-32-8)
- N-(5-((5-Chlorothiophen-2-yl)methyl)-1,3,4-oxadiazol-2-yl)-5-methylisoxazole-3-carboxamide (CAS 1020978-13-5)
- 5-Fluoro-1-(quinolin-4-yl)-1H-indole-3-carbonyl chloride (CAS 649550-99-2)
- Fraxamoside (CAS 326594-34-7)
- [5-methyl-1-(2-methylpropyl)-1h-pyrazol-4-yl]methanamine (CAS 1247814-97-6)
- 6-(Difluoromethoxy)pyridine-2-carbonitrile (CAS 1214349-26-4)
- 2-(Aminomethyl)-6-(trifluoromethyl)benzimidazole (CAS 944903-89-3)
- Carvedilol Impurity 33 D5 (CAS CATO-C4X-157433)
- 3-(2-Methoxypyridin-3-yl)-1-methyl-1h-pyrazol-5-amine (CAS 1339624-34-8)
- Benzyl 2-(difluoromethoxy)acetate (CAS 1089709-30-7)
- 1,5-Dibromo-2-chloro-4-methoxybenzene (CAS 174913-38-3)
- 3-(difluoromethyl)pyrrolidine hydrochloride (CAS 1376176-56-5)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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