Methyl 3-bromo-5-(hydroxymethyl)benzoate CAS 307353-32-8
| CAS No. | 307353-32-8 |
| Molecular Formula | C9H9BrO3 |
| Molecular Weight | 245.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 245.07 g/mol gives Methyl 3-bromo-5-(hydroxymethyl)benzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 3-bromo-5-(hydroxymethyl)benzoate (CAS 307353-32-8), molecular formula C9H9BrO3 and molecular weight 245.07 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 3-bromo-5-(hydroxymethyl)benzoate (C9H9BrO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9BrO3 |
| Molecular Weight | 245.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
Related Methyl Standards
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Recommended Standards
- Methyl 3-bromo-4-(hydroxymethyl)benzoate (CAS 90326-62-8)
- Methyl 3-bromo-5-hydroxy-2-methylbenzoate (CAS 2092700-79-1)
- Methyl 3-Bromo-2-methoxybenzoate (CAS 260806-90-4)
- Methyl 3-bromo-5-methoxybenzoate (CAS 56709-70-7)
- ZL0420, >98% (HPLC) (CAS 2230496-80-5)
- 1,2,3,4-Tetrahydroisoquinoline-5-carboxylic acid (CAS 1044764-16-0)
- N1-(4-(1,1-Dioxidoisothiazolidin-2-yl)phenyl)-N2-methyloxalamide (CAS 1087790-53-1)
- (11bR,11'bR)-4,4'-[(1S,2S)-1,2-Diphenyl-1,2-ethanediyl]bis[4,5-dihydro-3H-dinaphth[2,1-c:1',2'-e]azepine (CAS 1256952-84-7)
- Benzyl 9-hydroxy-3-azaspiro[5.5]undecane-3-carboxylate (CAS 1228949-40-3)
- 4-(4-Chlorophenyl)-1H-imidazole-2-carbaldehyde (CAS 944903-74-6)
- Posaconazole Impurity 112 (CAS 110931-77-6)
- 4-Fluoro-3-[(3-fluorophenyl)(hydroxy)methyl]phenylboronic acid (CAS 2377587-48-7)
- 5-(2-(Pentyloxy)benzylidene)-2-(pyridin-4-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 617694-61-8)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
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