Ribavirin Impurity N9 CAS 30747-23-0
| CAS No. | 30747-23-0 |
| Molecular Formula | C18H21N5O9 |
| Molecular Weight | 451.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ribavirin Impurity N9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Ribavirin Impurity N9 (CAS 30747-23-0, C18H21N5O9) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ribavirin Impurity N9 (C18H21N5O9) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H21N5O9 |
| Molecular Weight | 451.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 5 |
Related Ribavirin Standards
- Ribavirin Impurity 13 (CAS CATO-C4X-141313)
- Ribavirin Impurity 22 (CAS 7387-58-8)
- Ribavirin Impurity 12 (CAS 6979-94-8)
- Ribavirin 5-diphosphate lithium salt (CAS 63142-70-1)
- Ribavirin Impurity 34 (CAS CATO-C4X-141334)
- Ribavirin Impurity 35 (CAS CATO-C4X-141335)
- Ribavirin Impurity 11 (CAS 39925-10-5)
- Ribavirin Impurity 33 (CAS CATO-C4X-141333)
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