Brigatinib Impurity 2 CAS 1259274-28-6
| CAS No. | 1259274-28-6 |
| Molecular Formula | C21H28Cl2N6O |
| Molecular Weight | 451.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Brigatinib Impurity 2 (CAS 1259274-28-6), a pharmacopoeial impurity reference standard (molecular formula C21H28Cl2N6O, MW 451.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C21H28Cl2N6O, Brigatinib Impurity 2 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 451.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Brigatinib Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H28Cl2N6O |
| Molecular Weight | 451.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Brigatinib Standards
Recommended Standards
- Dotinurad Impurity 102 (CAS CATO-C4X-2494102)
- Ribavirin Impurity N9 (CAS 30747-23-0)
- Lansoprazole Impurity 39 (CAS 1187926-84-6)
- Deaminoethyl Fluvoxamine-β-D-Glucuronide (CAS 89035-93-8)
- Iohexol Impurity 32 (CAS CATO-C4X-166432)
- Vortioxetine Impurity 29 (CAS 609-60-9)
- Clopidogrel Impurity 79 (CAS CATO-C4X-102979)
- (E)-[(3,4-Dichlorophenyl)methoxy](1-{3-methyl-5-thia-2,7-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),3,6,8,10-pentaen-4-yl}ethylidene)amine (CAS 478063-13-7)
- 5-Ethylindole-3-carbaldehyde (CAS 68742-29-0)
- Cilostazol Impurity 9 (CAS 1796891-27-4)
- 2-(4-Amino-1h-pyrazol-1-yl)-N,N-diethylacetamide (CAS 1152841-61-6)
- Phenylbutazone Impurity 4 (CAS 30923-77-4)
- 2-Isopropyl-6-phenyl-3-pyridinecarboxylic acid ethyl ester, 97% (CAS 1198774-12-7)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com