7-Hydroxy-3-(m-tolyloxy)-2-(trifluoromethyl)-4H-chromen-4-one CAS 307544-90-7
| CAS No. | 307544-90-7 |
| Molecular Formula | C17H11F3O4 |
| Molecular Weight | 336.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 7-Hydroxy-3-(m-tolyloxy)-2-(trifluoromethyl)-4H-chromen-4-one (CAS 307544-90-7), a certified reference material (molecular formula C17H11F3O4, MW 336.26 g/mol) for analytical method development and quality control.
The molecular framework of 7-Hydroxy-3-(m-tolyloxy)-2-(trifluoromethyl)-4H-chromen-4-one (C17H11F3O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H11F3O4 |
| Molecular Weight | 336.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Hydroxy Standards
- 7-Hydroxy-3-(2-methoxyphenyl)-2-(trifluoromethyl)-4H-chromen-4-one (CAS 303119-53-1)
- 7-Hydroxy-3-(4-methoxyphenyl)-2-(trifluoromethyl)-4h-chromen-4-one (CAS 315233-63-7)
- 7-Hydroxy-3-(p-tolyloxy)-2-(trifluoromethyl)-4H-chromen-4-one (CAS 449745-82-8)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-fluoro-2-methylphenyl)thiophen-2-yl)boronate (CAS 1402227-73-9)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(4-fluoro-2-methylphenyl)thiophen-2-yl)boronate (CAS 1402227-74-0)
- 7-Hydroxy-5-{[(2,4,6-trifluorophenyl)sulfanyl]methyl}pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 1333756-53-8)
- 1-Hydroxy-N'-(3-methoxybenzoyl)-2-naphthohydrazide (CAS 332147-11-2)
- (E)-4-(4-Hydroxy-3-methylbut-2-en-1-yl)-1,2-diphenylpyrazolidine-3,5-dione (CAS 58670-70-5)
Recommended Standards
- Spiromustine (CAS 56605-16-4)
- 5-(((2,6-Dichlorobenzyl)sulfinyl)methyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 344271-66-5)
- 1-Deoxy-1-fluoro-β-D-glucopyranuronic Acid Methyl Ester Triacetate (CAS 116523-80-9)
- 5-(((2,4-Dichlorobenzyl)sulfinyl)methyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 344271-97-2)
- 536-40-3 Benzoic acid, p-chloro-, hydrazide (8CI) Benzoic acid, 4-chloro-, hydrazide (9CI) 4-Chlorobenzohydrazide p-Chlorobenzhydrazide 4-Chlorobenzhydrazide p-Chlorobenzohydrazide p-Chlorobenzoic acid, hydrazide 4-Chlorobenzoic acid, hydrazide p-Chlorobenzoic hydrazide p-Chlorobenzoyl hydrazide 4-Chlorobenzoyl hydrazide p-Chlorobenzoylhydrazine 4-Chlorobenzoylhydrazine EINECS 208-632-0 NSC 54990 (CAS 536-40-3)
- 1,6,8-Trimethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 302953-13-5)
- 1-[2-Hydroxy-6-(3-phenoxypropoxy)phenyl]ethanone (CAS 53874-01-4)
- 6-(4-Chlorophenyl)-2-methyl-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 200879-66-9)
- 2-Benzylpyrrolidine hydrochloride (CAS 936225-47-7)
- 2-((1-(Aminomethyl)cyclohexyl)oxy)ethan-1-ol (CAS 1492798-29-4)
- 3-Benzylpyrrolidine-3-carboxylic acid (CAS 1274864-27-5)
- 1,2,3,4-Tetramethyl-5-(trifluoromethyl)cyclopenta-1,3-diene (CAS 142701-59-5)
- 2-iodo-5,5-dimethylcyclohexane-1,3-dione (CAS 98593-03-4)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
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