7-Hydroxy-3-(naphthalen-1-yl)-2-(trifluoromethyl)-4H-chromen-4-one CAS 307544-91-8

Purity 97%+In StockPharmaceutical Standards
CAS No.307544-91-8
Molecular FormulaC20H11F3O3
Molecular Weight356.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Hydroxy-3-(naphthalen-1-yl)-2-(trifluoromethyl)-4H-chromen-4-one CAS 307544-91-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

7-Hydroxy-3-(naphthalen-1-yl)-2-(trifluoromethyl)-4H-chromen-4-one (CAS 307544-91-8), molecular formula C20H11F3O3 and molecular weight 356.29 g/mol, is a CATO reference standard with documented purity and traceability.

7-Hydroxy-3-(naphthalen-1-yl)-2-(trifluoromethyl)-4H-chromen-4-one (C20H11F3O3) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), 7-Hydroxy-3-(naphthalen-1-yl)-2-(trifluoromethyl)-4H-chromen-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H11F3O3
Molecular Weight356.29 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing

Related Hydroxy Standards

Recommended Standards

Why CATO?