(E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one CAS 307952-91-6
| CAS No. | 307952-91-6 |
| Molecular Formula | C22H25ClN2O4 |
| Molecular Weight | 416.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one.
(E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 307952-91-6) is a high-purity analytical reference standard with the molecular formula C22H25ClN2O4 and a molecular weight of 416.90 g/mol.
Based on its molecular formula C22H25ClN2O4, (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 416.90 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H25ClN2O4 |
| Molecular Weight | 416.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (CAS 647031-54-7)
- [(E)-2-(3-{[(4-chlorophenyl)methyl]sulfanyl}-6-methyl-1,2,4-triazin-5-yl)ethenyl][(3-fluorophenyl)methoxy]amine (CAS 338775-71-6)
- [(E)-2-(3-{[(4-chlorophenyl)methyl]sulfanyl}-6-methyl-1,2,4-triazin-5-yl)ethenyl][(4-fluorophenyl)methoxy]amine (CAS 338775-67-0)
- 1-(4-Chlorophenyl)-3-(2-methyl-2-((3-(trifluoromethyl)benzyl)thio)propyl)urea (CAS 882748-00-7)
- 14-(4-Chlorophenyl)-14H-benzo[7,8]chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione (CAS 1243382-80-0)
- N-(3-chlorophenyl)-4-methyl-N-(3-nitrobenzyl)benzenesulfonamide (CAS 332163-39-0)
- N-(4-chlorophenyl)-4-methyl-N-(4-nitrobenzyl)benzenesulfonamide (CAS 332156-65-7)
- 2-((5-(4-Chlorophenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-ethoxyphenyl)acetamide (CAS 332934-58-4)
Recommended Standards
- (2Z)-2-(Benzenesulfonyl)-3-{3-[(2-chloro-1,3-thiazol-5-yl)methoxy]phenyl}prop-2-enenitrile (CAS 866144-39-0)
- (S)-tert-Butyl (4-(3-chloro-2-(phenylcarbamoyl)phenyl)-3-oxobutan-2-yl)carbamate (CAS 1386861-47-7)
- 2-Chloro-3-(4-(2,6-dimethylmorpholine-4-carbonyl)piperidin-1-yl)naphthalene-1,4-dione (CAS 439108-68-6)
- Ethyl 2-((5-(3-(2-(4-chlorophenoxy)ethyl)ureido)-1,3,4-thiadiazol-2-yl)thio)acetate (CAS 866042-03-7)
- tert-Butyl 4-((bis(2-((3-chlorobenzyl)(cyclopropyl)amino)-2-oxoethyl)amino)methyl)piperidine-1-carboxylate (CAS 1353979-86-8)
- Boc-Sec(Mob)-OH (CAS 959415-39-5)
- N-((Cyclohexylimino)methylene)-N-methylcyclohexanaminium iodide (CAS 36049-77-1)
- 4-(Boc-amino)cyclohexanethiol (CAS 1353979-18-6)
- Fenbutatin Oxide (CAS 13356-08-6)
- 2-Cyano-N'-phenylacetohydrazide (CAS 60598-59-6)
- (R)-3-((acetamidomethyl)thio)-2-((tert-butoxycarbonyl)amino)-3-methylbutanoic acid (CAS 129972-45-8)
- 6-Chloro-2-phenylnicotinonitrile (CAS 1710661-31-6)
- 2-(Cyclopentylthio)-N-(2-(2-(thiophen-2-yl)thiazolo[3,2-b][1,2,4]triazol-6-yl)ethyl)acetamide (CAS 1327318-55-7)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
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