(E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one CAS 647031-54-7
| CAS No. | 647031-54-7 |
| Molecular Formula | C22H25ClN2O4 |
| Molecular Weight | 416.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (CAS 647031-54-7), a certified reference material (molecular formula C22H25ClN2O4, MW 416.90 g/mol) for analytical method development and quality control.
Structurally, (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (C22H25ClN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 416.90 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25ClN2O4 |
| Molecular Weight | 416.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 307952-91-6)
- [(E)-2-(3-{[(4-chlorophenyl)methyl]sulfanyl}-6-methyl-1,2,4-triazin-5-yl)ethenyl][(3-fluorophenyl)methoxy]amine (CAS 338775-71-6)
- [(E)-2-(3-{[(4-chlorophenyl)methyl]sulfanyl}-6-methyl-1,2,4-triazin-5-yl)ethenyl][(4-fluorophenyl)methoxy]amine (CAS 338775-67-0)
- 1-(4-Chlorophenyl)-3-(2-methyl-2-((3-(trifluoromethyl)benzyl)thio)propyl)urea (CAS 882748-00-7)
- 14-(4-Chlorophenyl)-14H-benzo[7,8]chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione (CAS 1243382-80-0)
- N-(3-chlorophenyl)-4-methyl-N-(3-nitrobenzyl)benzenesulfonamide (CAS 332163-39-0)
- N-(4-chlorophenyl)-4-methyl-N-(4-nitrobenzyl)benzenesulfonamide (CAS 332156-65-7)
- 2-((5-(4-Chlorophenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-ethoxyphenyl)acetamide (CAS 332934-58-4)
Recommended Standards
- (2Z)-2-(Benzenesulfonyl)-3-{3-[(2-chloro-1,3-thiazol-5-yl)methoxy]phenyl}prop-2-enenitrile (CAS 866144-39-0)
- (S)-tert-Butyl (4-(3-chloro-2-(phenylcarbamoyl)phenyl)-3-oxobutan-2-yl)carbamate (CAS 1386861-47-7)
- n,n-Dibenzyl-4-chloro-3-nitrobenzenesulfonamide (CAS 426223-67-8)
- 2-Chloro-3-(4-(2,6-dimethylmorpholine-4-carbonyl)piperidin-1-yl)naphthalene-1,4-dione (CAS 439108-68-6)
- (S)-2,2-Dimethylchroman-4-amine hydrochloride (CAS 2646585-67-1)
- 3-(2,6-Dichlorophenyl)propanoic acid (CAS 51656-68-9)
- 2,3-Dimethylbenzyl Alcohol (CAS 13651-14-4)
- (2E)-2-Cyano-3-(dimethylamino)-N'-[(2E)-5,5,5-trifluoro-4-oxopentan-2-ylidene]prop-2-enehydrazide (CAS 478064-02-7)
- Menaquinone impurity 23 (CAS 2387-69-1)
- 2-FLuoro-5-(propan-2-yl)phenol (CAS 1243279-91-5)
- N-((1,4-Dioxan-2-yl)methyl)-1-phenylmethanamine (CAS 937668-81-0)
- 5,15-Bis(4-ethynylphenyl)porphyrin (CAS 632301-81-6)
- 2-Chloro-1-{11,15-dioxa-16-azatetracyclo[8.7.0.0^{2,7}.0^{13,17}]heptadeca-1(10),2(7),3,5,8-pentaen-16-yl}ethan-1-one (CAS 477853-77-3)
- Des-Ser39-Tirzepatide (CAS CATO-CPTD788936)
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