Osimertinib Impurity 42 CAS 3086362-46-8
| CAS No. | 3086362-46-8 |
| Molecular Formula | C28H35N7O3 |
| Molecular Weight | 517.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Osimertinib Impurity 42 (CAS 3086362-46-8), a pharmacopoeial impurity reference standard (molecular formula C28H35N7O3, MW 517.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Osimertinib Impurity 42 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 517.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H35N7O3 |
| Molecular Weight | 517.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Nitrogen Atoms | 7 |
Related Osimertinib Standards
- Osimertinib Impurity 37 (CAS CATO-C4X-204537)
- Osimertinib Impurity 80 (CAS CATO-C4X-204580)
- Osimertinib Impurity 81 (CAS CATO-C4X-204581)
- Osimertinib Impurity 113 (CAS CATO-C4X-2045113)
- Osimertinib-4 (CAS 1805787-93-2)
- Osimertinib Impurity 24 (CAS CATO-C4X-204524)
- Osimertinib D6 (CAS 1638281-44-3)
- Osimertinib Impurity 60 (CAS CATO-C4X-204560)
Recommended Standards
- Brexpiprazole impurity 115 (CAS CATO-C4X-1131115)
- Pitavastatin Impurity 10(R,R) (CAS CATO-C4X-103710)
- Palbociclib Impurity 139 (CAS CATO-C4X-1125139)
- Pitavastatin Impurity 39 (CAS 154170-27-1)
- Glipizide Impurity 23 (CAS 41472-49-5)
- Azithromycin EP Impurity Q (CAS 2095879-65-3)
- Orforglipron Impurity 12 (CAS 2212021-81-1)
- Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-a-D-galactopyranoside (CAS 3554-91-4)
- Tetrakis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)silane (CAS 1448021-42-8)
- 4-Oxo-1-pentyl-1,4-dihydroquinoline-3-carboxylic acid (CAS 875148-76-8)
- Chlorhexidine Digluconate EP Impurity G HCl (CAS 152504-09-1 (free base))
- N-methoxy-N-methyl-2-(trifluoromethyl)benzamide (CAS 116332-63-9)
- L-Sorbose-4- (CAS 478506-34-2)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com