Ensifentrine impurity 45 CAS 3088358-10-2
| CAS No. | 3088358-10-2 |
| Molecular Formula | C12H9ClN2O3 |
| Molecular Weight | 264.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Ensifentrine impurity 45 (C12H9ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 264.66 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Ensifentrine impurity 45 (CAS 3088358-10-2) is a certified pharmaceutical impurity reference standard with the molecular formula C12H9ClN2O3 and a molecular weight of 264.66 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ensifentrine impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN2O3 |
| Molecular Weight | 264.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ensifentrine Standards
- Ensifentrine impurity 48 (CAS 20488-59-9)
- Ensifentrine impurity (CAS 4359-64-2)
- Ensifentrine impurity 7 (CAS 91209-79-9)
- Ensifentrine Impurity 27 (CAS CATO-C4X-335327)
- Ensifentrine impurity 44 (CAS CATO-C4X-335344)
- Ensifentrine impurity 46 (CAS CATO-C4X-335346)
- Ensifentrine impurity 50 (CAS 39201-71-3)
- Ensifentrine Impurity 26 (CAS CATO-C4X-335326)
Recommended Standards
- 7428-60-6 2-Trisilanol, 1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)- DTXSID70402456 (CAS 7428-60-6)
- Aclonifen (CAS 74070-46-5)
- Methyl 5-chloro-4-formyl-1-phenyl-1H-pyrazole-3-carboxylate (CAS 401571-11-7)
- Fenridazon (CAS 68254-10-4)
- Valsartan Impurity 139 (CAS 72907-79-0)
- Palbociclib Impurity 54 (CAS CATO-C4X-112554)
- Lenvatinib Impurity 19 (CAS 417724-81-3)
- 4-Deoxy-4-fluoro-D-mannose (CAS 87764-47-4)
- 1,6-Dimethyl-1,1,2,2,3,3,4,4,5,5,6,6-dodecaphenylhexasilane (CAS 1586-77-2)
- Tert-butyl n-(3,4-difluorophenyl)carbamate (CAS 144298-04-4)
- N-(2-((4-bromophenyl)sulfonyl)ethyl)-2-((4-chlorophenyl)sulfonyl)propanamide (CAS 337923-67-8)
- 3-(Methoxymethyl)-1-propyl-1H-pyrazole (CAS 1474090-51-1)
- H-Ala-Ala-Phe-AMC (free base) (CAS 62037-41-6)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com