Valsartan Impurity 139 CAS 72907-79-0
| CAS No. | 72907-79-0 |
| Molecular Formula | C24H26BrO2P |
| Molecular Weight | 457.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C24H26BrO2P, Valsartan Impurity 139 contains a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 457.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Valsartan Impurity 139 (CAS 72907-79-0), a pharmacopoeial impurity reference standard (molecular formula C24H26BrO2P, MW 457.34 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Valsartan Impurity 139 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H26BrO2P |
| Molecular Weight | 457.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Br-containing |
Related Valsartan Standards
- Valsartan Impurity 53 (CAS 137863-42-4)
- Valsartan N-Oxide 2 (CAS CATO-C4X-1057148)
- Valsartan Impurity 149 (CAS CATO-C4X-1057149)
- Valsartan Impurity 4 (Mixture of Diastereomers) (CAS 188259-69-0)
- Valsartan N-Oxide (CAS CATO-C4X-105779)
- Valsartan Impurity 115 (CAS CATO-C4X-1057115)
- Valsartan Impurity 9 (CAS 1111177-30-0)
- Valsartan Impurity 106 (CAS CATO-C4X-1057106)
Recommended Standards
- 444579-42-4 Tributyl(4-hexylthiophen-2-yl)stannane DTXSID10623800 (CAS 444579-42-4)
- N3-PEG4-C2-Pfp ester (CAS 1353012-00-6)
- 7-Bromo-5-phenyl-4-(phenylsulfonyl)-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one (CAS 314047-09-1)
- 4-(2,3-Dichlorophenyl)-N-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide (CAS 493017-18-8)
- Aztreonam impurity 100 (CAS CATO-C4X-1522100)
- Prilocaine impurity 42 (CAS CATO-C4X-193442)
- Lifitegrast Impurity 129 (CAS 2605229-68-1)
- 2-[2-[4-[2-methoxy-5-[2-(2-pyridyl)ethyl]phenoxy]phenyl]ethyl]pyridine (CAS 365542-43-4)
- 2-(Allyloxy)-3-methylbenzenesulfonamide (CAS 82020-84-6)
- 5-Ethynyl-1-(1-methylethyl)-1H-pyrazole (CAS 1690560-11-2)
- tert-Butyl 5-methoxy-2-oxospiro[indoline-3,4-piperidine]-1-carboxylate (CAS 752234-64-3)
- 7-(2-bromoethoxy)-4-methyl-2H-chromen-2-one (CAS 7471-76-3)
- (1R-cis)-N-[2-amino-4-chloro-6-[[4-(hydroxymethyl)-2-cyclopenten-1-yl]amino]-5-pyrimidinyl]-formamide (CAS 171887-04-0)
- Peptide 433 (CAS CATO-CPTD788433)
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