6-(Tert-butyl)-2-((2-chlorobenzyl)thio)-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile CAS 309278-44-2
| CAS No. | 309278-44-2 |
| Molecular Formula | C27H27ClN2S |
| Molecular Weight | 447.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(Tert-butyl)-2-((2-chlorobenzyl)thio)-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile.
6-(Tert-butyl)-2-((2-chlorobenzyl)thio)-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 309278-44-2), molecular formula C27H27ClN2S and molecular weight 447.03 g/mol, is a CATO reference standard with documented purity and traceability.
6-(Tert-butyl)-2-((2-chlorobenzyl)thio)-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (C27H27ClN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(Tert-butyl)-2-((2-chlorobenzyl)thio)-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H27ClN2S |
| Molecular Weight | 447.03 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- 3-((4-(Tert-butyl)benzyl)thio)-1-(4-chlorophenyl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 691868-86-7)
- 2-Bromo-5-(tributylstannyl)pyridine (CAS 1008756-65-7)
- 7-Chloro-3-(2-ethyl-5-fluoro-4-((2-(trimethylsilyl)ethoxy)methoxy)phenyl)-4-methyl-2,6-naphthyridine (CAS 1956371-18-8)
- (6-Bromopyridin-2-yl)-tributylstannane (CAS 189083-81-6)
- 4-Ethoxy-2-(methylthio)aniline (CAS 647843-13-8)
- 3-(1H-imidazol-4-yl)propanenitrile hydrochloride (CAS 40836-07-5)
- Sodium arsenate heptahydrate (CAS 7778-43-0)
- Limaprost Impurity 8 (CAS CATO-C4X-21458)
- (3R)-octahydropyrido[2,1-c][1,4]oxazine-3-carbonitrile (CAS 1461698-13-4)
- 2-Chloro-N-(4-fluoro-2-methylphenyl)acetamide (CAS 366-44-9)
- (4-Fluoro-3-phenoxyphenyl)methanol (CAS 68359-53-5)
- 2-(Tert-butoxycarbonyl)-8-oxo-2,7-diazaspiro[3.5]Nonane-5-carboxylic acid (CAS 1357352-68-1)
- Levocarnitine Impurity 21 (CAS CATO-C4X-129221)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
Why CATO?
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