7-Chloro-3-(2-ethyl-5-fluoro-4-((2-(trimethylsilyl)ethoxy)methoxy)phenyl)-4-methyl-2,6-naphthyridine CAS 1956371-18-8
| CAS No. | 1956371-18-8 |
| Molecular Formula | C23H28ClFN2O2Si |
| Molecular Weight | 447.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Chloro-3-(2-ethyl-5-fluoro-4-((2-(trimethylsilyl)ethoxy)methoxy)phenyl)-4-methyl-2,6-naphthyridine (CAS 1956371-18-8), molecular formula C23H28ClFN2O2Si and molecular weight 447.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-Chloro-3-(2-ethyl-5-fluoro-4-((2-(trimethylsilyl)ethoxy)methoxy)phenyl)-4-methyl-2,6-naphthyridine (C23H28ClFN2O2Si) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-3-(2-ethyl-5-fluoro-4-((2-(trimethylsilyl)ethoxy)methoxy)phenyl)-4-methyl-2,6-naphthyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H28ClFN2O2Si |
| Molecular Weight | 447.02 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- (3-Iodophenyl)acetyl chloride (CAS 127109-66-4)
- 3-Amino-6-cyanobenzofuran-2-carboxylic acid (CAS 1823903-87-2)
- Ethyl 5-methoxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylate (CAS 2114311-60-1)
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- Tenofovir disoproxil Impurity 16(See C4X-107650) (CAS CATO-C4X-107616)
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