6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylic acid CAS 31009-06-0

Purity 97%+In StockPharmaceutical Standards
CAS No.31009-06-0
Molecular FormulaC11H5F4NO2
Molecular Weight259.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylic acid CAS 31009-06-0 chemical structure

Description

The occurrence of 6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylic acid (CAS 31009-06-0), molecular formula C11H5F4NO2 and molecular weight 259.16 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylic acid (C11H5F4NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 259.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H5F4NO2
Molecular Weight259.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1965
Halogen ContentF-containing
Nitrogen Atoms1

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