1-(3-Nitrophenyl)pyrrolidine-2,5-dione CAS 31036-66-5
| CAS No. | 31036-66-5 |
| Molecular Formula | C10H8N2O4 |
| Molecular Weight | 220.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-Nitrophenyl)pyrrolidine-2,5-dione.
CATO supplies 1-(3-Nitrophenyl)pyrrolidine-2,5-dione (CAS 31036-66-5), a certified reference material (molecular formula C10H8N2O4, MW 220.18 g/mol) for analytical method development and quality control.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 1-(3-Nitrophenyl)pyrrolidine-2,5-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O4 |
| Molecular Weight | 220.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 2 |
Related Nitrophenyl Standards
- [2-(4-nitrophenyl)-1,3-oxazol-5-yl]methanol (CAS 1315365-55-9)
- 3-(3-Methyl-4-nitrophenyl)-1,2-oxazol-5-ol (CAS 1354924-07-4)
- 5-Methyl-4-(3-nitrophenyl)-4H-1,2,4-triazol-3-ol (CAS 1420537-71-8)
- 1-(2-Nitrophenyl)pyrrolidine-2,5-dione (CAS 18377-52-1)
- (1-(4-Nitrophenyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 90886-87-6)
- (3-(3-Nitrophenyl)isoxazol-5-yl)methanol (CAS 438565-35-6)
- (5-(4-Nitrophenyl)-1,3,4-oxadiazol-2-yl)methanamine (CAS 944897-70-5)
- 1-(4-Nitrophenyl)pyrrolidine-2,5-dione (CAS 35488-92-7)
Recommended Standards
- 1-(3-methoxyphenyl)imidazolidine-2,4,5-trione (CAS 929971-79-9)
- 1-(4-Methoxyphenyl)imidazolidine-2,4,5-trione (CAS 852956-32-2)
- [4-(1H-Tetrazol-1-yl)phenoxy]acetic acid (CAS 832740-47-3)
- [3-(4-Nitro-phenyl)-isoxazol-5-yl]-methanol (CAS 605663-76-1)
- 4-Bromo-n1,n1-dimethylbenzene-1,2-diamine hydrochloride (CAS 1177271-06-5)
- Nintedanib Impurity 31 (CAS 4316-33-0)
- N3-PEG3-C2-NHS ester (CAS 1245718-89-1)
- 3-((tert-Butoxycarbonyl)amino)-4-methylbenzoic acid (CAS 231958-04-6)
- Methyl (2S,4S)-4-(3-fluorophenoxy)-2-pyrrolidinecarboxylate (CAS 1217606-19-3)
- 2-((3,3-Dimethylcyclohexyl)amino)propan-1-ol (CAS 1498799-15-7)
- 1-Bromo-2-chloro-4-methyl-3-nitrobenzene (CAS 1402836-12-7)
- 2-Chloro-9-methyl-7H-purin-8(9H)-one (CAS 1273315-11-9)
- Resmetirom Impurity 51 (CAS CATO-C4X-291251)
- Exenatide Acetate (CAS 141732-76-5)
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