Nintedanib Impurity 31 CAS 4316-33-0
| CAS No. | 4316-33-0 |
| Molecular Formula | C11H16O4 |
| Molecular Weight | 212.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 212.24 g/mol gives Nintedanib Impurity 31 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nintedanib Impurity 31 (CAS 4316-33-0), molecular formula C11H16O4 and molecular weight 212.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Nintedanib Impurity 31 (C11H16O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Nintedanib Impurity 31 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16O4 |
| Molecular Weight | 212.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Nintedanib Standards
- Nintedanib Impurity 30 (CAS 60743-21-7)
- Nintedanib Impurity 161 (CAS 98953-48-1)
- Nintedanib Impurity 98 (CAS 1860012-61-8)
- Nintedanib Impurity 165 (CAS 1351810-29-1)
- Nintedanib Impurity 37 (CAS 14719-83-6)
- Nintedanib Impurity 156 (CAS 1040320-04-4)
- Nintedanib Impurity N11 (CAS 91362-61-7)
- Nintedanib Impurity N12 (CAS 22911-21-3)
Recommended Standards
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- 4-Methyl-1-(pyridin-4-yl)-3,4-dihydroisoquinoline (CAS 87870-23-3)
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Why CATO?
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