5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 310451-80-0
| CAS No. | 310451-80-0 |
| Molecular Formula | C15H10F3N3O3 |
| Molecular Weight | 337.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 310451-80-0), a certified reference material (molecular formula C15H10F3N3O3, MW 337.25 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 337.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10F3N3O3 |
| Molecular Weight | 337.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methoxyphenyl Standards
- 5-(2-Methoxyphenyl)-3-(4-(trifluoromethyl)pyridin-2-yl)-1,3,4-oxadiazol-2(3H)-one (CAS 883010-12-6)
- 5-(2-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 831229-13-1)
- 5-(3-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 524036-15-5)
- 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 333761-72-1)
- 797809-13-3 5-(3-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid MFCD02253979 (CAS 797809-13-3)
- (E)-1-(4-Methoxyphenyl)-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanimine (CAS 380151-91-7)
- 8-(2-Methoxyphenyl)-5,12,14-trioxa-2-azatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),3(7),10,15-tetraen-6-one (CAS 866050-82-0)
- 3-Acetyl-1-(4-methoxyphenyl)-2-methyl-1H-indol-5-yl acetate (CAS 119953-11-6)
Recommended Standards
- Ethyl 5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 338777-85-8)
- 3-(6-Methyl-4-oxo-2-(trifluoromethyl)quinazolin-3(4H)-yl)-3-azabicyclo[3.1.0]Hexane-2,4-dione (CAS 866156-52-7)
- 88218-67-1 Benzoic acid--8-bromo-3,7-dimethylocta-2,6-dien-1-ol (1/1) DTXSID50829647 (CAS 88218-67-1)
- 2-Bromo-7-tert-butylpyrene (CAS 78751-80-1)
- 2-Bromo-3-methylbutenoic acid methyl ester 4627AE 51263-40-2 C6H9BrO2 (CAS 51263-40-2)
- Sodium 4-(benzhydrylamino)-4-oxobutanoate (CAS 2126161-32-6)
- n-(4-(n-Butylsulfamoyl)phenyl)acetamide (CAS 72225-61-7)
- Dibenzo[b,d]furan-2-ylhydrazine (CAS 412925-78-1)
- Methyl 2,3-difluoro-5-methoxyphenylacetate (CAS 1806331-02-1)
- 3,4,5-Trichlorobenzenesulfonamide (CAS 150729-70-7)
- 8-fluoro-1H,2H,3H,4H,5H-pyrido[4,3-b]indole (CAS 39876-39-6)
- 4-Methyl-N-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)-N-tosylbenzenesulfonamide (CAS 1333222-50-6)
- Dotinurad Impurity 223 (CAS CATO-C4X-2494223)
- (D-Ala2)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 444073-04-5)
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