5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 310451-82-2
| CAS No. | 310451-82-2 |
| Molecular Formula | C14H7F4N3O2 |
| Molecular Weight | 325.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 310451-82-2) is a high-purity analytical reference standard with the molecular formula C14H7F4N3O2 and a molecular weight of 325.22 g/mol.
The molecular framework of 5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C14H7F4N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7F4N3O2 |
| Molecular Weight | 325.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- 7-(4-Fluorophenyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 1245807-65-1)
- 5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo-[1,5-a]pyrimidine-3-carboxylic acid (CAS 310451-83-3)
- trans-4-[2-(3-fluorophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid (CAS 736136-55-3)
- 5-(2-Fluorophenyl)-2-((2-fluorophenyl)ethynyl)-4-hydroxy-6H-1,3-oxazin-6-one (CAS 1956331-58-0)
- 5-(3-Fluorophenyl)-2-((3-fluorophenyl)ethynyl)-4-hydroxy-6H-1,3-oxazin-6-one (CAS 1956376-36-5)
- 5-(4-Fluorophenyl)-2-((4-fluorophenyl)ethynyl)-4-hydroxy-6H-1,3-oxazin-6-one (CAS 1956376-41-2)
- 9-(4-Fluorophenyl)-6,9-dihydro-[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one (CAS 861208-09-5)
- [Acetyl-[4-(4-Fluorophenyl)Phenyl]Amino] Hydrogen Sulfate (CAS 132884-69-6)
Recommended Standards
- 4-(4-(3-Bromophenyl)thiazol-2-yl)morpholine (CAS 940802-31-3)
- 4-(2,4-Dichlorophenyl)-5-(1-methyl-1H-pyrrol-2-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 668471-48-5)
- 5-Bromo-N-methyl-N-((3-methylthiophen-2-yl)methyl)nicotinamide (CAS 940821-72-7)
- 2-Bromo-N-(4-isopropylthiazol-2-yl)benzamide (CAS 941175-72-0)
- 6-(4-Methoxyphenyl)hexanoic acid (CAS 107228-87-5)
- 4-[(3-Methoxyphenyl)sulfanyl]-2-(methylsulfanyl)quinazoline (CAS 477845-90-2)
- 6-Bromo-2,2-dimethylchroman-4-carbonitrile (CAS 1956331-54-6)
- 4-(Difluoromethyl)-6-methylpyridine-2,5-diol (CAS 1804713-04-9)
- 2-(5-Methoxy-1H-indol-2-yl)ethan-1-amine (CAS 69732-61-2)
- 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1082066-33-8)
- rac 1-Oleoyl-2-palmitoylglycerol (CAS 3331-34-8)
- Isavuconazole Impurity 194 (CAS CATO-C4X-1236194)
- (1E)-1-[2-(3,4-Difluorophenoxy)phenyl]-N-(4-iodophenyl)methanimine (CAS 477886-91-2)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788692)
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