1-(2-Chlorobenzyl)-1h-benzo[d]imidazole-2-thiol CAS 312290-68-9

Purity 97%+In StockPharmaceutical Standards
CAS No.312290-68-9
Molecular FormulaC14H11ClN2S
Molecular Weight274.77 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-Chlorobenzyl)-1h-benzo[d]imidazole-2-thiol CAS 312290-68-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 274.77 g/mol gives 1-(2-Chlorobenzyl)-1h-benzo[d]imidazole-2-thiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(2-Chlorobenzyl)-1h-benzo[d]imidazole-2-thiol (CAS 312290-68-9), molecular formula C14H11ClN2S and molecular weight 274.77 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(2-Chlorobenzyl)-1h-benzo[d]imidazole-2-thiol (C14H11ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2-Chlorobenzyl)-1h-benzo[d]imidazole-2-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H11ClN2S
Molecular Weight274.77 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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