Cyproheptadine impurity 12 CAS 31232-24-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.31232-24-3
Molecular FormulaC20H19NO
Molecular Weight289.37 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cyproheptadine impurity 12 CAS 31232-24-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 289.37 g/mol gives Cyproheptadine impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Cyproheptadine impurity 12 (CAS 31232-24-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H19NO and a molecular weight of 289.37 g/mol.

The molecular framework of Cyproheptadine impurity 12 (C20H19NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Cyproheptadine impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H19NO
Molecular Weight289.37 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1965
Nitrogen Atoms1

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