Calcitriol Impurity 2 CAS 103656-40-2
| CAS No. | 103656-40-2 |
| Molecular Formula | C28H46O3 |
| Molecular Weight | 430.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 430.66 g/mol gives Calcitriol Impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Calcitriol Impurity 2 (CAS 103656-40-2), a pharmacopoeial impurity reference standard (molecular formula C28H46O3, MW 430.66 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Calcitriol Impurity 2 (C28H46O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H46O3 |
| Molecular Weight | 430.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 85+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
Related Calcitriol Standards
Recommended Standards
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- Palbociclib Impurity 86 (CAS 2363172-64-7)
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- 4-(4-Chlorophenyl)tetrahydro-2h-pyran-4-amine hydrochloride (CAS 1439899-34-9)
- 1-(4-(4,6-Dimethylbenzo[d]thiazol-2-yl)piperazin-1-yl)butan-1-one (CAS 897484-49-0)
- 2H-Oxazolo[4,5-e]indole (CAS 77482-56-5)
- 2,2,2-Trifluoro-1-{1-[tris(propan-2-yl)silyl]-1h-pyrrol-3-yl}ethan-1-one (CAS 130408-88-7)
- (Z)-3-(Hydroxyimino)butan-2-one (CAS 110828-81-4)
- Peptide 442 (CAS CATO-CPTD788442)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com