4-hydroxy-N-methylpyridine-3-carboxamide CAS 3128-29-8
| CAS No. | 3128-29-8 |
| Molecular Formula | C7H8N2O2 |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-hydroxy-N-methylpyridine-3-carboxamide.
4-hydroxy-N-methylpyridine-3-carboxamide (CAS 3128-29-8) is a high-purity analytical reference standard with the molecular formula C7H8N2O2 and a molecular weight of 152.15 g/mol.
Structurally, 4-hydroxy-N-methylpyridine-3-carboxamide (C7H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 152.15 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-hydroxy-N-methylpyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O2 |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related hydroxy Standards
- 3-Hydroxy-2-methyl-d3-benzoic Acid (CAS 1020719-51-0)
- 6-Hydroxy-1,4-benzodioxane (CAS 10288-72-9)
- 3-Hydroxy-N-methylpicolinamide (CAS 1196-30-1)
- 2-Hydroxy-4-(hydroxymethyl)benzaldehyde (CAS 156605-23-1)
- 2-Hydroxy-5-methylnicotinamide (CAS 1822892-18-1)
- 4-hydroxy-2-methoxybenzaldehyde (CAS 18278-34-7)
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- 1-Acetyl-4-hydroxy-2,5-dihydro-1H-pyrrole-3-carbonitrile (CAS 18721-38-5)
Recommended Standards
- 4-Hydroxymethyl-benzoic acid (CAS 96937-45-0)
- 4-Methoxy-6-methylpyrimidine-2-carbaldehyde (CAS 92675-57-5)
- 2,4-Dihydroxy-6-methylbenzaldehyde (CAS 487-69-4)
- 4-Methoxynicotinamide (CAS 7418-64-6)
- 2,3-Dimethyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 933725-60-1)
- (S)-2-Amino-N-isopropyl-3-methyl-N-(pyrazin-2-ylmethyl)butanamide (CAS 1353997-38-2)
- Ethyl 3-({[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]carbonyl}amino)benzoate (CAS 897739-23-0)
- MI-77301 (CAS 1303607-60-4)
- 2-(Benzyloxy)-5-(trifluoromethyl)benzaldehyde (CAS 632626-08-5)
- 5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-amine (CAS 1443979-45-0)
- Dapagliflozin Impurity 102 (CAS CATO-C4X-1138102)
- 2-(2-(Cyclohex-1-en-1-yl)ethyl)-1,3-dioxoisoindoline-5-carboxylic acid (CAS 356573-34-7)
- [2-(phenoxymethyl)phenyl]boronic acid (CAS 729558-57-0)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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