5-(4-Bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid CAS 312922-08-0
| CAS No. | 312922-08-0 |
| Molecular Formula | C14H7BrF3N3O2 |
| Molecular Weight | 386.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (C14H7BrF3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-(4-Bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 312922-08-0) is a high-purity analytical reference standard with the molecular formula C14H7BrF3N3O2 and a molecular weight of 386.12 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(4-Bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7BrF3N3O2 |
| Molecular Weight | 386.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromophenyl Standards
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- 2,2-Bis(4-bromophenyl)-2-hydroxyacetic acid (CAS 30738-49-9)
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Recommended Standards
- 3-Bromo-5-phenyl-7-(trifluoromethyl)pyrazolo-[1,5-a]pyrimidine-2-carboxylic acid (CAS 304687-28-3)
- Memantine impurity 50 (CAS CATO-C4X-105850)
- 22306-37-2 Bismuth acetate Bismuth triacetate Acetic acid, bismuth(3+) salt EINECS 244-904-5 HSDB 2186 NSC 370498 (CAS 22306-37-2)
- Ixazomib Impurity 44 (CAS CATO-C4X-126744)
- (2S,4R)-Benzyl 4-(trifluoromethyl)pyrrolidine-2-carboxylate hydrochloride (CAS 2755813-03-5)
- 8-(Tert-butyl) 6-methyl 2-oxo-8-azabicyclo[3.2.1]Octane-6,8-dicarboxylate (CAS 228573-75-9)
- tert-Butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate (CAS 1276666-10-4)
- 1-(6-Bromo-1H-benzo[d]imidazol-2-yl)-2-methylpropan-1-amine (CAS 1178830-22-2)
- 3-Bromobenzo[c]phenanthrene (CAS 54113-65-4)
- 2-Amino-5,5-dimethylhexanamide (CAS 1467452-84-1)
- 4-(Aminomethyl)-6-(difluoromethyl)-3-hydroxypicolinic acid (CAS 1806948-55-9)
- N-[2-(4-Isopropylphenyl)ethyl]-N-methylamine (CAS 137069-28-4)
- 2-(3-(Isopropyl(methyl)amino)pyrrolidin-1-yl)ethanol (CAS 1353982-07-6)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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