Ixazomib Impurity 44 CAS CATO-C4X-126744
| CAS No. | CATO-C4X-126744 |
| Molecular Formula | C18H26BCl2NO3 |
| Molecular Weight | 386.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ixazomib Impurity 44 (CAS CATO-C4X-126744, C18H26BCl2NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ixazomib Impurity 44 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 386.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Ixazomib Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H26BCl2NO3 |
| Molecular Weight | 386.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ixazomib Standards
- Ixazomib Impurity 16 (CAS CATO-C4X-126716)
- Ixazomib Impurity 17 (CAS CATO-C4X-126717)
- Ixazomib Impurity 18 (CAS CATO-C4X-126718)
- Ixazomib-13C2,15N (CAS CATO-C4X-126764)
- Ixazomib Impurity 81 (CAS CATO-C4X-126781)
- Ixazomib (CAS 1072833-77-2)
- Ixazomib Impurity 3 (CAS CATO-C4X-12673)
- Ixazomib Impurity 77 (CAS CATO-C4X-126777)
Recommended Standards
- Memantine impurity 50 (CAS CATO-C4X-105850)
- 1H,1H,7H-Dodecafluoroheptyl acrylate 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl acrylate trihydroperfluoroheptyl acrylate 1h,1h,7h-perfluoroheptyl acrylate 1h,1h,7h perfluoroheptyl acrylate 2993-85-3 (CAS 2993-85-3)
- 5-(4-Bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 312922-08-0)
- Bromfenac Impurity 35 (CAS CATO-C4X-200235)
- Prednisone EP Impurity C (CAS 70522-55-3)
- Epinephrine Impurity 85 (CAS CATO-C4X-184985)
- Edaravone Impurity 52 (CAS CATO-C4X-106252)
- 1-(2,5-Dihydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (CAS 6342-92-3)
- n-(1-(Furan-2-yl)ethyl)-4-methylpyridin-3-amine (CAS 1344055-09-9)
- (S)-2-methyl-1-(3,4,5-trifluorophenyl)propan-1-amine (CAS 1213027-39-4)
- 1-(3,8-Diazabicyclo[4.2.0]Octan-8-yl)ethan-1-one (CAS 1824106-56-0)
- Mirabegron Impurity 61 (CAS 18699-02-0)
- Bifendate impurity 11 (CAS CATO-C4X-255511)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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