8-(Trifluoromethyl)quinolin-2(1H)-one CAS 920494-30-0
| CAS No. | 920494-30-0 |
| Molecular Formula | C10H6F3NO |
| Molecular Weight | 213.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 8-(Trifluoromethyl)quinolin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 8-(Trifluoromethyl)quinolin-2(1H)-one (CAS 920494-30-0), a certified reference material (molecular formula C10H6F3NO, MW 213.16 g/mol) for analytical method development and quality control.
8-(Trifluoromethyl)quinolin-2(1H)-one (C10H6F3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H6F3NO |
| Molecular Weight | 213.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
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- 5-(Trifluoromethyl)-1H-indole-7-carbaldehyde (CAS 1100215-34-6)
- 6-(Trifluoromethyl)-1H-indole-4-carbaldehyde (CAS 1100215-61-9)
- 4-(4-(Trifluoromethyl)phenyl)oxazole (CAS 1126636-40-5)
- 7-Trifluoromethyl-[1,8]naphthyridin-2-ylamine (CAS 1146081-30-2)
- 6-(Trifluoromethyl)isoquinolin-3-ol (CAS 1175271-49-4)
- 8-(Trifluoromethyl)isoquinolin-3-ol (CAS 1175271-71-2)
Recommended Standards
- 7-(Trifluoromethyl)quinoxalin-2-amine (CAS 59489-42-8)
- Ethyl 2-fluoro-4-nitrobenzoate (CAS 363-32-6)
- 7-(Trifluoromethyl)quinolin-8-ol (CAS 313-17-7)
- Ethyl 2-fluoro-5-nitrobenzoate (CAS 367-79-3)
- (2S)-2-[[[[(1S,2S)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N-(diphenylmethyl)-N,3,3-trimethylbutanamide (CAS 1421697-46-2)
- N-Benzyl-5-bromo-4-mercapto-N-methylpyridine-3-sulfonamide (CAS 1352541-01-5)
- N,2-Dimethyl-3-propyl-N-(undec-10-en-1-yl)quinolin-4-amine (CAS 88484-73-5)
- 4-(5-((4-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole (CAS 955976-78-0)
- 4-Methyl-3-(2,2,2-trifluoroethoxy)-5H-pyrido[1’,2’:4,5][1,2,4]thiadiazino[2,3-a]benzimidazol-13-ium Chloride (CAS 111712-17-5)
- 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine Dihydrochloride (CAS 157327-51-0)
- Tricyclohexyl Borate (CAS 2467-16-5)
- 6-Amino-3-propyl-4-(quinolin-4-yl)-2H,4H-pyrano[2,3-c]pyrazole-5-carbonitrile (CAS 489403-88-5)
- Ethyl 6-(difluoromethoxy)-4-methylnicotinate (CAS 1079352-16-1)
- Semaglutide Impurity 123 (CAS 71997-93-8)
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