Methyl 7-(trifluoromethyl)-5,6-dihydrobenzo-[h]pyrazolo[5,1-b]quinazoline-10-carboxylate CAS 313389-78-5
| CAS No. | 313389-78-5 |
| Molecular Formula | C17H12F3N3O2 |
| Molecular Weight | 347.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 347.29 g/mol gives Methyl 7-(trifluoromethyl)-5,6-dihydrobenzo-[h]pyrazolo[5,1-b]quinazoline-10-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methyl 7-(trifluoromethyl)-5,6-dihydrobenzo-[h]pyrazolo[5,1-b]quinazoline-10-carboxylate (CAS 313389-78-5), a certified reference material (molecular formula C17H12F3N3O2, MW 347.29 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 7-(trifluoromethyl)-5,6-dihydrobenzo-[h]pyrazolo[5,1-b]quinazoline-10-carboxylate (C17H12F3N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 7-(trifluoromethyl)-5,6-dihydrobenzo-[h]pyrazolo[5,1-b]quinazoline-10-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12F3N3O2 |
| Molecular Weight | 347.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- N-(4-{[2-(trifluoromethyl)quinazolin-4-yl]oxy}phenyl)acetamide (CAS 341964-16-7)
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Recommended Standards
- Methyl 3-(pyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-4-carboxylate (CAS 400076-48-4)
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- N-Phenyl-2-(2-(trifluoromethyl)quinazolin-4-yl)hydrazinecarboxamide (CAS 414891-74-0)
- Diethyl 2-(trifluoromethoxy)phenylamino-N-methylenemalonate (CAS 49713-41-9)
- 4-((4-Acetylpiperazin-1-yl)methyl)benzoic acid hydrochloride (CAS 1211327-33-1)
- 4-(6-Bromo-2-oxo-2H-chromene-3-amido)benzoic acid (CAS 312756-47-1)
- N-(3-acetylphenyl)-2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole-4-carboxamide (CAS 957037-27-3)
- 7433-56-9 trans-Dec-5-ene 5-Decene, (E)- 4-01-00-00902 (Beilstein Handbook Reference) BRN 1719487 (E)-5-Decene trans-5-Decene EINECS 231-080-7 NSC 95430 (CAS 7433-56-9)
- 2-(Aminomethyl)-5-bromo-3-fluoropyridine (CAS 1234616-19-3)
- N1-Azepan-4-yl-N2,N2-dimethylglycinamide dihydrochloride (CAS 2108705-42-4)
- [(2R)-1-aminopropan-2-yl]diethylamine (CAS 1807920-87-1)
- 5-Chloro-m-xylene (CAS 556-97-8)
- 5-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-N-(1H-indol-4-yl)furan-2-carboxamide (CAS 1574325-70-4)
- Peptide 436 (CAS CATO-CPTD788436)
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