2-{[1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]sulfanyl}pyridine CAS 338420-54-5
| CAS No. | 338420-54-5 |
| Molecular Formula | C15H8F3N5S |
| Molecular Weight | 347.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-{[1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]sulfanyl}pyridine (C15H8F3N5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-{[1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]sulfanyl}pyridine (CAS 338420-54-5), molecular formula C15H8F3N5S and molecular weight 347.32 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H8F3N5S |
| Molecular Weight | 347.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related trifluoromethyl Standards
- Benzyl 2-(4-(trifluoromethyl)phenyl)-2,5-dihydro-1H-pyrrole-1-carboxylate (CAS 1956381-99-9)
- Methyl 7-(trifluoromethyl)-5,6-dihydrobenzo-[h]pyrazolo[5,1-b]quinazoline-10-carboxylate (CAS 313389-78-5)
- N-(4-{[2-(trifluoromethyl)quinazolin-4-yl]oxy}phenyl)acetamide (CAS 341964-16-7)
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Recommended Standards
- 2-[4-(difluoromethyl)-6-(4-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937607-18-6)
- 4-(5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)pentanamido)-2-hydroxybenzoic acid (CAS 4113-89-7)
- 2-[4-(difluoromethyl)-6-(3-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937607-17-5)
- 4-Fluoro-N-(4-methoxy-6-nitrobenzo[d]thiazol-2-yl)benzamide (CAS 313404-31-8)
- 1-(3-Chloro-4-fluorophenyl)-5-methoxy-1H-pyrazole-3-carboxylic acid (CAS 1239734-47-4)
- 2-Fluoro-4-oxazolecarboxylic Acid (CAS 1167056-76-9)
- 2-[3-(chlorosulfonyl)phenyl]acetic acid (CAS 1314911-30-2)
- [1-(2-fluorophenyl)piperidin-4-yl]methanol (CAS 1005502-75-9)
- 1-{4-[3-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]phenyl}-1,4-dihydropyridin-4-one (CAS 866144-91-4)
- 1,1'-Bis(di-tert-butylphosphino)ferrocene 84680-95-5 1,1'-BIS(DI-T-BUTYLPHOSPHINO)FERROCENE;1,1'-BIS(DI-TERT-BUTYLPHOSPHINO)FERROCENE;1,1'-BIS[BIS(1,1-DIMETHYLETHYL)PHOSPHINO]FERROCENE;BIS[(DI-TERT-BUTYLPHOSPHINO)CYCLOPENTADIENYL]IRON;DBTPF GC10032 (CAS 84680-95-5)
- 6-Hydroxy-4-methyl-2-oxo-2H-chromen-7-yl acetate (CAS 46895-13-0)
- 2-(2-Methyl-1,3-dioxolan-2-yl)acetic acid (CAS 5735-97-7)
- (-)-(S)-N-Norreticuline (-)-Norreticuline (1S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-7-isoquinolinol (S)-Norreticuline 2-Demethylreticuline 4781-58-2 Nor Reticuline Norreticuline (CAS 4781-58-2)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
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