Terazosin EP Impurity M CAS 31350-27-3
| CAS No. | 31350-27-3 |
| Molecular Formula | C14H14N2O4 |
| Molecular Weight | 274.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 274.27 g/mol gives Terazosin EP Impurity M distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Terazosin EP Impurity M (CAS 31350-27-3, C14H14N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Terazosin EP Impurity M (C14H14N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14N2O4 |
| Molecular Weight | 274.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 2 |
Related Terazosin Standards
- Terazosin EP Impurity O (CAS 547730-06-3)
- Terazosin Hydrochloride Dihydrate EP Impurity O (CAS CATO-C4X-134929)
- Terazosin RC 2 (CAS 113534-03-5)
- Terazosin EP Impurity M (CAS 31350-28-4)
- Terazosin Impurity 4 (CAS 20197-86-8)
- Terazosin Impurity 18 (CAS CATO-C4X-134918)
- Terazosin EP Impurity D (CAS 102714-74-9)
- Terazosin Impurity 33 (CAS 2470438-57-2)
Recommended Standards
- (3aR,4S,9bS)-6-Methyl-7-nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid 956523-14-1 (CAS 956523-14-1)
- Lenalidomide Impurity 34 (CAS CATO-C4X-190334)
- (3aR,4S,9bS)-6-Methyl-9-nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid 956247-29-3 (CAS 956247-29-3)
- Travoprost Impurity 12 (CAS 39746-01-5)
- Midazolam Impurity 15 (CAS 59468-73-4)
- Levocetirizine Impurity 74 (CAS 705289-62-9（free base）)
- Difelikefalin Impurity 64 (CAS 2269512-88-9)
- N-(5-(N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)sulfamoyl)-4-methylthiazol-2-yl)acetamide (CAS 1335106-03-0)
- 6-(Benzyloxy)-7-methoxyisochroman-3-one (CAS 113697-05-5)
- (7-Methoxyquinolin-3-yl)methanol (CAS 568594-17-2)
- (E)-4-((2-Methylallyl)oxy)-3-(2,2,2-trifluoro-1-(2-((2-(trifluoromethyl)phenyl)sulfonyl)hydrazono)ethyl)benzyl acetate (CAS 2738683-73-1)
- 2-Aminothiazol-4-ol hydrochloride (CAS 857969-63-2)
- 3-Phenyl-6-(thiophen-2-yl)isoxazolo[5,4-b]pyridine-4-carbohydrazide (CAS 937599-65-0)
- Liraglutide-d8 Tritrifluoroacetate (CAS CATO-C4X-199223)
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