Terazosin Impurity 18 CAS CATO-C4X-134918
| CAS No. | CATO-C4X-134918 |
| Molecular Formula | C10H9ClN2O3 |
| Molecular Weight | 240.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Terazosin Impurity 18 (CAS CATO-C4X-134918), a pharmacopoeial impurity reference standard (molecular formula C10H9ClN2O3, MW 240.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H9ClN2O3, Terazosin Impurity 18 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 240.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN2O3 |
| Molecular Weight | 240.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Terazosin Standards
- Terazosin Impurity 4 (CAS 20197-86-8)
- Terazosin Impurity 33 (CAS 2470438-57-2)
- Terazosin EP Impurity M (CAS 31350-27-3)
- Terazosin EP Impurity O (CAS 547730-06-3)
- Terazosin Hydrochloride Dihydrate EP Impurity O (CAS CATO-C4X-134929)
- Terazosin RC 2 (CAS 113534-03-5)
- Terazosin EP Impurity N (CAS 63074-07-7)
- Terazosin Hydrochloride Dihydrate EP Impurity N (CAS 412334-56-6)
Recommended Standards
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- Methyl 18-fluorooctadecanoate (CAS 463-29-6)
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