PD 118057 CAS 313674-97-4
| CAS No. | 313674-97-4 |
| Molecular Formula | C21H17Cl2NO2 |
| Molecular Weight | 386.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 386.27 g/mol gives PD 118057 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies PD 118057 (CAS 313674-97-4), a certified reference material (molecular formula C21H17Cl2NO2, MW 386.27 g/mol) for analytical method development and quality control.
The molecular framework of PD 118057 (C21H17Cl2NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H17Cl2NO2 |
| Molecular Weight | 386.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- N-benzyl-3,4-dichloro-N-(4-methoxyphenyl)benzamide (CAS 338400-66-1)
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- Methyl 2-{[4-(3,4-dichlorophenyl)piperazino]carbonyl}-3-(dimethylamino)acrylate (CAS 303151-73-7)
- Bendamustine impurity 42 (CAS CATO-C4X-127142)
- 5,7-dimethyl-4-oxo-4H-chromene-3-carbonitrile (CAS 286832-89-1)
- (1S,4R)-4-Amino-2-cyclopenten-1-carboxylic Acid HCl (CAS 134234-04-1)
- (R)-tert-Butyl 2-amino-2-(4-hydroxyphenyl)acetate (CAS 501692-32-6)
- 4-amino-3-methyl-1,3-benzoxazol-2-one (CAS 99584-80-2)
- Bumetanide Impurity 116 (CAS CATO-C4X-1986116)
- 3-((2,4-Dichlorobenzyl)oxy)benzoic acid (CAS 360778-55-8)
- 1-tert-Butoxycarbonylindazole-3-boronic acid (CAS 1315339-92-4)
- Toxoflavin (CAS 84-82-2)
- H-Ala-D-Ala-Ala-OH (CAS 5874-86-2)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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