Methyl 2-{[4-(3,4-dichlorophenyl)piperazino]carbonyl}-3-(dimethylamino)acrylate CAS 303151-73-7
| CAS No. | 303151-73-7 |
| Molecular Formula | C17H21Cl2N3O3 |
| Molecular Weight | 386.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 2-{[4-(3,4-dichlorophenyl)piperazino]carbonyl}-3-(dimethylamino)acrylate (CAS 303151-73-7) is a high-purity analytical reference standard with the molecular formula C17H21Cl2N3O3 and a molecular weight of 386.27 g/mol.
Methyl 2-{[4-(3,4-dichlorophenyl)piperazino]carbonyl}-3-(dimethylamino)acrylate (C17H21Cl2N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 2-{[4-(3,4-dichlorophenyl)piperazino]carbonyl}-3-(dimethylamino)acrylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H21Cl2N3O3 |
| Molecular Weight | 386.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- (2Z)-1-(2,4-Dichlorophenyl)-3-[4-(dimethylamino)phenyl]-2-(1H-imidazol-1-yl)prop-2-en-1-one (CAS 313548-47-9)
- 1-(3,4-Dichlorophenyl)-3-((4-phenoxyphenyl)amino)propan-1-one (CAS 477320-62-0)
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- 3-(2,6-Dichlorophenyl)-5-[(E)-2-[(4-hydroxy-2-methylphenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (CAS 338402-72-5)
- 3-(2,6-Dichlorophenyl)-5-[(E)-2-[(4-methoxyphenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (CAS 338402-68-9)
- 3-{3-[(2,4-dichlorophenyl)methoxy]thiophen-2-yl}-4-methyl-5-(methylsulfanyl)-4H-1,2,4-triazole (CAS 343375-94-0)
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Recommended Standards
- 5-((4-Bromobenzyl)thio)imidazo[1,2-c]quinazolin-2(3H)-one (CAS 478046-05-8)
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- 4-(Benzyloxy)-2-chloro-N-(4-chlorobenzyl)benzamide (CAS 478046-43-4)
- PD 118057 (CAS 313674-97-4)
- Methyl 5-((8-methoxy-2-methyl-4-oxoquinolin-1(4H)-yl)methyl)furan-2-carboxylate (CAS 1216643-46-7)
- 1-(2,6-Bis(trifluoromethyl)pyridin-4-yl)ethan-1-one (CAS 1393568-10-9)
- 2-Methyl-6-(3-methyl-1H-pyrazol-1-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1352239-72-5)
- 4-Chloro-2-fluoro-2-piperidinomethyl benzophenone (CAS 898773-63-2)
- 4-(2,5-Dimethylphenyl)butanoic acid (CAS 1453-06-1)
- (R)-2-Amino-4,4,4-trifluoro-butyric acid ethyl ester hydrochloride (CAS 2408437-80-7)
- N,N＇-Bis-(3,4-Dichlorophenyl)Urea (CAS 4300-43-0)
- Dapagliflozin Impurity 154 (CAS CATO-C4X-1138154)
- 1-(Pyridin-2-yl)-1h-1,2,4-triazol-5-amine (CAS 1247628-46-1)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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