3-((4-Hydroxyphenyl)(methyl)amino)benzo[d]isothiazole 1,1-dioxide CAS 314036-10-7

Purity 97%+In StockPharmaceutical Standards
CAS No.314036-10-7
Molecular FormulaC14H12N2O3S
Molecular Weight288.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-((4-Hydroxyphenyl)(methyl)amino)benzo[d]isothiazole 1,1-dioxide CAS 314036-10-7 chemical structure

Description

3-((4-Hydroxyphenyl)(methyl)amino)benzo[d]isothiazole 1,1-dioxide (CAS 314036-10-7), molecular formula C14H12N2O3S and molecular weight 288.32 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-((4-Hydroxyphenyl)(methyl)amino)benzo[d]isothiazole 1,1-dioxide (C14H12N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-((4-Hydroxyphenyl)(methyl)amino)benzo[d]isothiazole 1,1-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H12N2O3S
Molecular Weight288.32 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2
Sulfur Atoms1

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