1-(4-Hydroxyphenyl)-4-(piperidine-1-carbonyl)pyrrolidin-2-one CAS 5477-87-2

Purity 97%+In StockPharmaceutical Standards
CAS No.5477-87-2
Molecular FormulaC16H20N2O3
Molecular Weight288.34 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Hydroxyphenyl)-4-(piperidine-1-carbonyl)pyrrolidin-2-one CAS 5477-87-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

1-(4-Hydroxyphenyl)-4-(piperidine-1-carbonyl)pyrrolidin-2-one (CAS 5477-87-2), molecular formula C16H20N2O3 and molecular weight 288.34 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(4-Hydroxyphenyl)-4-(piperidine-1-carbonyl)pyrrolidin-2-one (C16H20N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

CATO manufactures 1-(4-Hydroxyphenyl)-4-(piperidine-1-carbonyl)pyrrolidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H20N2O3
Molecular Weight288.34 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Nitrogen Atoms2

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