5-(4-Chlorophenyl)pyrimidine-2-thiol CAS 31408-24-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-Chlorophenyl)pyrimidine-2-thiol.

5-(4-Chlorophenyl)pyrimidine-2-thiol (CAS 31408-24-9) is a high-purity analytical reference standard with the molecular formula C10H7ClN2S and a molecular weight of 222.69 g/mol.

5-(4-Chlorophenyl)pyrimidine-2-thiol (C10H7ClN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(4-Chlorophenyl)pyrimidine-2-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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