3-(4-Fluorophenyl)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one CAS 315233-72-8

Purity 97%+In StockPharmaceutical Standards
CAS No.315233-72-8
Molecular FormulaC16H8F4O3
Molecular Weight324.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Fluorophenyl)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one CAS 315233-72-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

3-(4-Fluorophenyl)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one (CAS 315233-72-8) is a high-purity analytical reference standard with the molecular formula C16H8F4O3 and a molecular weight of 324.23 g/mol.

3-(4-Fluorophenyl)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one (C16H8F4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

CATO manufactures 3-(4-Fluorophenyl)-7-hydroxy-2-(trifluoromethyl)-4h-chromen-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H8F4O3
Molecular Weight324.23 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing

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