Vonoprazan Impurity 209 CAS 31543-47-2
| CAS No. | 31543-47-2 |
| Molecular Formula | C8H8BrFO |
| Molecular Weight | 219.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Vonoprazan Impurity 209 (CAS 31543-47-2), a pharmacopoeial impurity reference standard (molecular formula C8H8BrFO, MW 219.05 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Vonoprazan Impurity 209 (C8H8BrFO) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Vonoprazan Impurity 209 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8BrFO |
| Molecular Weight | 219.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F/Br-containing |
Related Vonoprazan Standards
- Vonoprazan Impurity 138 (CAS CATO-C4X-1020138)
- Vonoprazan Impurity 261 (CAS CATO-C4X-1020261)
- Vonoprazan Impurity 283 (CAS CATO-C4X-1020283)
- Vonoprazan Impurity 288 (CAS CATO-C4X-1020288)
- Vonoprazan Impurity N27 (CAS 24367-50-8)
- Vonoprazan Impurity 306 (CAS CATO-C4X-1020306)
- Vonoprazan Fumarate Impurity 60 (CAS CATO-C4X-102060)
- Vonoprazan Fumarate Impurity 62 (CAS CATO-C4X-102062)
Recommended Standards
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- 1-(2-(Methylsulfonyl)ethyl)cyclobutan-1-amine (CAS 1538879-52-5)
- 5-Amino-2-fluoro-n,n-dimethylbenzamide (CAS 682757-75-1)
- Tetraethylammonium formate (CAS 38410-12-7)
- 5-Amino-2,3-dihydro-1H-indene-1-carboxylic acid (CAS 61346-48-3)
- 1-(7-Methyl-1h-indol-3-yl)butan-2-amine (CAS 13712-80-6)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com