1-(3,5-Dichloropyridin-2-yl)thiourea CAS 31545-32-1
| CAS No. | 31545-32-1 |
| Molecular Formula | C6H5Cl2N3S |
| Molecular Weight | 222.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(3,5-Dichloropyridin-2-yl)thiourea (CAS 31545-32-1), molecular formula C6H5Cl2N3S and molecular weight 222.09 g/mol, is a CATO reference standard with documented purity and traceability.
1-(3,5-Dichloropyridin-2-yl)thiourea (C6H5Cl2N3S) contains a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5Cl2N3S |
| Molecular Weight | 222.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dichloropyridin Standards
- 3-((3,5-Dichloropyridin-2-yl)oxy)propan-1-amine (CAS 1248268-27-0)
- N1-(3,5-Dichloropyridin-2-yl)propane-1,3-diamine (CAS 92993-52-7)
- 3-(4,6-Dichloropyridin-3-yl)oxetan-3-ol (CAS 1613239-16-9)
- 1-(4,6-Dichloropyridin-3-yl)-2,2-difluoroethan-1-one (CAS 2229238-42-8)
- 1-(2,4-Dichloropyridin-3-yl)-2-methylpropan-1-one (CAS 1260535-73-6)
- 1-(4,6-Dichloropyridin-3-yl)-2-methylpropan-1-one (CAS 2355769-48-9)
- 2-(3,5-Dichloropyridin-2-yl)-2,2-difluoroethan-1-ol (CAS 1431842-80-6)
- 2-(2,6-Dichloropyridin-4-yl)-2,2-difluoroethan-1-ol (CAS 2228800-04-0)
Recommended Standards
- (4-Butoxy-3,5-dimethylphenyl)boronic acid (CAS 845551-41-9)
- 1,2-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole (CAS 2223050-13-1)
- (3-(3,3-Dimethylbutoxy)phenyl)boronic acid (CAS 945837-59-2)
- 1,3-Dimethylpyrazole-5-boronic Acid Pinacol Ester (CAS 847818-79-5)
- PF-06281355 (CAS 1435467-38-1)
- 2-[(pyridin-2-yl)methyl]cyclopentan-1-amine (CAS 1368170-47-1)
- 4-Fluoro-5-methoxyisoindoline (CAS 1427363-57-2)
- 2-aminofuran-3-carbonitrile (CAS 139370-56-2)
- 4-(Difluoromethyl)-6-fluoro-3-methyl-2-(trifluoromethyl)pyridine (CAS 1806972-79-1)
- 2-Bromo-3-methyl-N-(m-tolyl)butanamide (CAS 391220-18-1)
- 3-Iodo-1H-indole-2-carbonitrile (CAS 51796-65-7)
- Clopidogrel Impurity 90 (CAS 1251736-86-3)
- [4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methylsulfinyl)-5-pyrimidinyl]-ethyl Ester-d6 (CAS 1189487-47-5)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
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