4-Chloro-5-methylisoxazol-3(2H)-one CAS 31554-94-6
| CAS No. | 31554-94-6 |
| Molecular Formula | C4H4ClNO2 |
| Molecular Weight | 133.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Chloro-5-methylisoxazol-3(2H)-one is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 133.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 4-Chloro-5-methylisoxazol-3(2H)-one (CAS 31554-94-6), a certified reference material (molecular formula C4H4ClNO2, MW 133.53 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-5-methylisoxazol-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H4ClNO2 |
| Molecular Weight | 133.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (3-Chloro-1,2-oxazol-5-yl)methanol (CAS 105175-03-9)
- 5-Chloro-1H-1,2,4-triazole-3-methanol (CAS 385377-24-2)
- 5-Chloro-2-methyl-1,2-dihydro-3H-1,2,4-triazol-3-one (CAS 22354-86-5)
- 2-Chloro-N-cyclopropylacetamide (CAS 19047-31-5)
- 3-Chloro-1-methyl-2-pyrrolidinone (CAS 208585-67-5)
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- 4-Chloro-2-hydroxy-2-methylbutanenitrile (CAS 717127-31-6)
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Recommended Standards
- (2-Chlorooxazol-4-yl)methanol (CAS 706789-06-2)
- 5-(Chloromethyl)isoxazol-3(2H)-one (CAS 2682-41-9)
- 4-Chloroaniline-<SUP>13</SUP>C<SUB>6</SUB> (CAS 1313734-69-8)
- N-Chlorosuccinimide (CAS 128-09-6)
- 2-((1-((Benzyloxy)carbonyl)piperidin-3-yl)(cyclopropyl)amino)acetic acid (CAS 1353960-68-5)
- 2,2-Dimethyl-1,3-dichloropropane (CAS 29559-55-5)
- 5-Bromo-1,3-dichloro-2-(3-isopropyl-4-methoxyphenoxy)benzene (CAS 525575-58-0)
- 2-Chloro-3-cyclopropylpyrazine (CAS 136819-11-9)
- 4-Chloro-1-trityl-1H-pyrrolo[2,3-b]pyridine (CAS 2438941-56-9)
- 5-(4-(2-Methoxyethoxy)phenyl)oxazole-2-carboxylic acid (CAS 1352496-59-3)
- 3-(4-Isobutylphenyl)-1-(2-methoxyphenyl)-1H-pyrazole-5-carboxylic acid (CAS 618382-75-5)
- Tert-butyl (2,2,3,3-tetrafluoropropyl) carbonate (CAS 1980035-09-3)
- (2E)-2-{4-[5-(2,4-dichlorophenyl)furan-2-yl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]prop-2-enenitrile (CAS 338978-48-6)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com