5-(Chloromethyl)isoxazol-3(2H)-one CAS 2682-41-9
| CAS No. | 2682-41-9 |
| Molecular Formula | C4H4ClNO2 |
| Molecular Weight | 133.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 133.53 g/mol gives 5-(Chloromethyl)isoxazol-3(2H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(Chloromethyl)isoxazol-3(2H)-one (CAS 2682-41-9), molecular formula C4H4ClNO2 and molecular weight 133.53 g/mol, is a CATO reference standard with documented purity and traceability.
5-(Chloromethyl)isoxazol-3(2H)-one (C4H4ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(Chloromethyl)isoxazol-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H4ClNO2 |
| Molecular Weight | 133.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 5-(Chloromethyl)-1,3,4-oxadiazol-2-amine (CAS 1277183-21-7)
- (R)-5-(Chloromethyl)pyrrolidin-2-one (CAS 138541-53-4)
- (S)-5-(Chloromethyl)pyrrolidin-2-one (CAS 72479-04-0)
- 1-(Chloromethyl)pyrrolidin-2-one (CAS 31282-95-8)
- 5-(Chloromethyl)-3-methyl-4,5-dihydroisoxazole (CAS 69578-12-7)
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- 3-(Chloromethyl)isothiazole (CAS 1246549-42-7)
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Recommended Standards
- 4-Chloro-5-methylisoxazol-3(2H)-one (CAS 31554-94-6)
- N-Chlorosuccinimide (CAS 128-09-6)
- (2-Chlorooxazol-4-yl)methanol (CAS 706789-06-2)
- 4-Chlorophenylamine-13C6 (CAS 89059-39-2)
- 2-Amino-N'-(propan-2-ylidene)benzohydrazide (CAS 53131-21-8)
- 4-Methoxyphenyl 2-3-4-6-tetra-O-benzyl-β-D-galactopyranoside (CAS 143536-99-6)
- 184683-37-2 (Ala6,D-Trp8,L-alaninol15)-Galanin (1-15) MFCD01318880 (CAS 184683-37-2)
- 4-(3-Phenylpropyl)pyridin-2-amine (CAS 84824-94-2)
- Nintedanib Impurity 169 (CAS CATO-C4X-1814169)
- (3-(5-Fluoropyridin-2-yl)phenyl)methanol (CAS 1349716-24-0)
- 5-methyl-1-phenyl-1H-pyrazol-3-amine (CAS 85485-59-2)
- 4,5-Epoxy-19-nortestosterone (CAS 52153-24-9)
- N-(2-Amino-6-methylphenyl)-5-methylisoxazole-3-carboxamide (CAS 145440-95-5)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
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