Quetiapine EP Impurity G CAS 3159-07-7
| CAS No. | 3159-07-7 |
| Molecular Formula | C13H9NOS |
| Molecular Weight | 227.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Quetiapine EP Impurity G (CAS 3159-07-7) is a certified pharmaceutical impurity reference standard with the molecular formula C13H9NOS and a molecular weight of 227.28 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, Quetiapine EP Impurity G is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 227.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Quetiapine EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9NOS |
| Molecular Weight | 227.28 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Quetiapine Standards
- Quetiapine EP Impurity U (CAS 5786-26-5)
- Quetiapine Impurity 26 (CAS 13509-33-6)
- Quetiapine Impurity 54 (CAS 4171-83-9)
- Quetiapine Impurity 85 (CAS 141691-24-9)
- Quetiapine impurity 78 (CAS 936094-62-1)
- Quetiapine-d8 HemifumarateDISCONTINUED. Please see Q510002. (CAS 1031703-36-2)
- Quetiapine impurity 83 (CAS 2101854-40-2)
- Quetiapine Impurity N2 (CAS 20290-48-6)
Recommended Standards
- Amisulpride Impurity 66 (CAS CATO-C4X-104566)
- 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3 (CAS 210049-13-1)
- Amisulpride Impurity 24 (CAS 81487-05-0)
- 2-(2-Hydroxyphenyl)benzothiazole (CAS 3411-95-8)
- Isavuconazole Impurity 37 Chloride DiHCl (Mixture of Diastereomers) (CAS CATO-C4X-123637)
- Xanomeline Impurity 35 Fumarate (CAS CATO-C4X-330135)
- Sivelestat Impurity 15 (CAS 526-21-6)
- 5-(Difluoromethoxy)benzo[d]oxazol-2-amine (CAS 1806532-29-5)
- 7-Methoxy-5-methylbenzo[c][1,2]oxaborol-1(3H)-ol (CAS 195821-87-5)
- Adenosine Impurity 27 (CAS 103828-77-9)
- 4-(1,3-Thiazol-2-yl)oxan-4-amine (CAS 1250166-85-8)
- (R)-N-Methyl-2,2,2-trifluoro-1-phenylethylamine (CAS 1389310-24-0)
- Methyl 3-acetamido-4,5-dichlorothiophene-2-carboxylate (CAS 632356-39-9)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
Why CATO?
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