Cyanocobalamin /Vitamin B12 Impurity 17 CAS 3171-45-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.3171-45-7
Molecular FormulaC8H12N2
Molecular Weight136.19 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cyanocobalamin /Vitamin B12 Impurity 17 CAS 3171-45-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cyanocobalamin /Vitamin B12 Impurity 17.

Cyanocobalamin /Vitamin B12 Impurity 17 (CAS 3171-45-7) is a certified pharmaceutical impurity reference standard with the molecular formula C8H12N2 and a molecular weight of 136.19 g/mol.

The molecular framework of Cyanocobalamin /Vitamin B12 Impurity 17 (C8H12N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Cyanocobalamin /Vitamin B12 Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H12N2
Molecular Weight136.19 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms2

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