rel-tert-Butyl (2S,4R)-4-fluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate CAS 317356-90-4
| CAS No. | 317356-90-4 |
| Molecular Formula | C10H18FNO3 |
| Molecular Weight | 219.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies rel-tert-Butyl (2S,4R)-4-fluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 317356-90-4), a certified reference material (molecular formula C10H18FNO3, MW 219.25 g/mol) for analytical method development and quality control.
The molecular framework of rel-tert-Butyl (2S,4R)-4-fluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate (C10H18FNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H18FNO3 |
| Molecular Weight | 219.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- methyl 2-fluoro-2-(2-methoxy-4-pyridyl)propanoate (CAS 2755892-82-9)
- Tert-butyl ((3-(fluoromethyl)oxetan-3-yl)methyl)carbamate (CAS 2306276-76-4)
- 8-(tert-Butyl)-3-fluoroquinolin-2-ol (CAS 518070-27-4)
- tert-Butyl (2R,4R)-4-fluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 869527-51-5)
- Hydrocortisone 21-Butyrate (CAS 6677-99-2)
- 4-(2-Chloroethyl)thiomorpholine (CAS 63906-73-0)
- 2-methoxy-6-methylpyridine-4-carbonitrile (CAS 1256825-69-0)
- Colchicine EP Impurity D (CAS 477-29-2)
- 4-Acetamido-2-methoxy-5-nitrobenzoic acid (CAS 59338-94-2)
- 5-(2-Chlorophenyl)-2-fluorobenzoic acid (CAS 1184837-79-3)
- 2,4-Dichloro-6-(methoxymethoxy)benzoic acid (CAS 2624417-34-9)
- 4-((5-(Trifluoromethyl)pyridin-2-yl)thio)butanenitrile (CAS 1019596-15-6)
- Pethidine EP Impurity D (CAS 28030-27-5)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com