Colchicine EP Impurity D CAS 477-29-2
| CAS No. | 477-29-2 |
| Molecular Formula | C27H33NO11 |
| Molecular Weight | 547.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Colchicine EP Impurity D (CAS 477-29-2) is a certified pharmaceutical impurity reference standard with the molecular formula C27H33NO11 and a molecular weight of 547.55 g/mol.
Colchicine EP Impurity D (C27H33NO11) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Colchicine EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H33NO11 |
| Molecular Weight | 547.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Colchicine Standards
- Colchicine Methanethiosulfonate (CAS 1217821-52-7)
- Colchicine Impurity 13 (CAS CATO-C4X-141113)
- Colchicine-d6 (CAS 1217651-73-4)
- iso-Colchicine-d3 (CAS 1246818-69-8)
- Colchicine-d3 (CAS 1217625-62-1)
- Colchicine Racemic Mixture Impurity (CAS 54192-66-4)
- rac-Colchicine, >98% (CAS 209810-38-8)
- (R)-Colchicine (CAS 75520-89-7)
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- Deoxycholic acid Impurity 22 (CAS 3360-89-2)
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- 2-(5-Chloro-3-methylpyridin-2-yl)ethan-1-amine (CAS 1393570-70-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com