3,3'-(Methylenebis(thiazole-2,4-diyl))bis(2H-chromen-2-one) CAS 319491-51-5
| CAS No. | 319491-51-5 |
| Molecular Formula | C25H14N2O4S2 |
| Molecular Weight | 470.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,3'-(Methylenebis(thiazole-2,4-diyl))bis(2H-chromen-2-one) (CAS 319491-51-5), molecular formula C25H14N2O4S2 and molecular weight 470.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3,3'-(Methylenebis(thiazole-2,4-diyl))bis(2H-chromen-2-one) (C25H14N2O4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,3'-(Methylenebis(thiazole-2,4-diyl))bis(2H-chromen-2-one) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H14N2O4S2 |
| Molecular Weight | 470.52 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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Recommended Standards
- 2-(2,5-Dioxo-2',3'-dihydrospiro[imidazolidine-4,1'-inden]-1-yl)-N-(4-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)phenyl)acetamide (CAS 794563-97-6)
- Diisopropyl 3-benzoyl-7-(pyridin-4-yl)indolizine-1,2-dicarboxylate (CAS 853334-28-8)
- (S)-2-(4-(((9H-fluoren-9-yl)methoxy)carbonyl)-3-benzyl-2-oxopiperazin-1-yl)acetic acid (CAS 959583-57-4)
- Methyl 1-benzyl-3-(4-methoxyphenyl)-4,6-dioxo-5-phenyloctahydropyrrolo[3,4-c]pyrrole-1-carboxylate (CAS 318239-69-9)
- 4-Cyano-5-methoxy-1H-indazole (CAS 1352395-32-4)
- Benzhydrylamine (CAS 91-00-9)
- N-[5-[4-[(6-Cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-α]pyridin-2-yl]cyclopropanecarboxamide (CAS 1206101-20-3)
- 2-chloro-5-(6-chloro-1,3-benzothiazol-2-yl)aniline (CAS 1461714-56-6)
- 5-(Thiophen-3-ylmethyl)-1,3,4-oxadiazol-2-amine (CAS 1042654-57-8)
- (3-((4-Chlorobenzyl)oxy)phenyl)boronic acid (CAS 870778-90-8)
- (4-Chloro-2-((tetrahydrofuran-3-yl)oxy)pyrimidin-5-yl)boronic acid (CAS 2225152-62-3)
- 3-Fluoro-N-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)benzamide (CAS 508230-01-1)
- 2-Isopropyl-6-(piperidin-4-yl)pyrimidin-4-amine (CAS 1710472-13-1)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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